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IMGN853, a Folate Receptor-α (FRα)-Targeting Antibody-Drug Conjugate, Exhibits Potent Targeted Antitumor Activity against FRα-Expressing Tumors.
Ab, Olga; Whiteman, Kathleen R; Bartle, Laura M; Sun, Xiuxia; Singh, Rajeeva; Tavares, Daniel; LaBelle, Alyssa; Payne, Gillian; Lutz, Robert J; Pinkas, Jan; Goldmacher, Victor S; Chittenden, Thomas; Lambert, John M.
Afiliación
  • Ab O; Department of Cell Biology, ImmunoGen, Inc., Waltham, Massachusetts. olga.ab@immunogen.com.
  • Whiteman KR; Department of Pharmacology Toxicology, ImmunoGen, Inc., Waltham, Massachusetts.
  • Bartle LM; Department of Cell Biology, ImmunoGen, Inc., Waltham, Massachusetts.
  • Sun X; Department of Biochemistry, ImmunoGen, Inc., Waltham, Massachusetts.
  • Singh R; Department of Biochemistry, ImmunoGen, Inc., Waltham, Massachusetts.
  • Tavares D; Department of Antibody Engineering, ImmunoGen, Inc., Waltham, Massachusetts.
  • LaBelle A; Department of Biomarkers, ImmunoGen, Inc., Waltham, Massachusetts.
  • Payne G; Department of Bioanalytical Science, ImmunoGen, Inc., Waltham, Massachusetts.
  • Lutz RJ; Department of Translational Research and Development, ImmunoGen, Inc., Waltham, Massachusetts.
  • Pinkas J; Department of Pharmacology Toxicology, ImmunoGen, Inc., Waltham, Massachusetts.
  • Goldmacher VS; Department of Cell Biology, ImmunoGen, Inc., Waltham, Massachusetts.
  • Chittenden T; Research and Development, ImmunoGen, Inc., Waltham, Massachusetts.
  • Lambert JM; Research and Development, ImmunoGen, Inc., Waltham, Massachusetts.
Mol Cancer Ther ; 14(7): 1605-13, 2015 Jul.
Article en En | MEDLINE | ID: mdl-25904506
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Inmunoconjugados / Ensayos Antitumor por Modelo de Xenoinjerto / Receptor 1 de Folato / Anticuerpos Monoclonales / Neoplasias Tipo de estudio: Prognostic_studies Límite: Animals / Female / Humans Idioma: En Revista: Mol Cancer Ther Asunto de la revista: ANTINEOPLASICOS Año: 2015 Tipo del documento: Article Pais de publicación: Estados Unidos
Texto completo
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Imprimir
XML
PubMed Links
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Inmunoconjugados / Ensayos Antitumor por Modelo de Xenoinjerto / Receptor 1 de Folato / Anticuerpos Monoclonales / Neoplasias Tipo de estudio: Prognostic_studies Límite: Animals / Female / Humans Idioma: En Revista: Mol Cancer Ther Asunto de la revista: ANTINEOPLASICOS Año: 2015 Tipo del documento: Article Pais de publicación: Estados Unidos