Phosphoethanolamine Transferase LptA in Haemophilus ducreyi Modifies Lipid A and Contributes to Human Defensin Resistance In Vitro.

Trombley, Michael P; Post, Deborah M B; Rinker, Sherri D; Reinders, Lorri M; Fortney, Kate R; Zwickl, Beth W; Janowicz, Diane M; Baye, Fitsum M; Katz, Barry P; Spinola, Stanley M; Bauer, Margaret E

Trombley, Michael P; Post, Deborah M B; Rinker, Sherri D; Reinders, Lorri M; Fortney, Kate R; Zwickl, Beth W; Janowicz, Diane M; Baye, Fitsum M; Katz, Barry P; Spinola, Stanley M; Bauer, Margaret E.

Afiliación

Trombley MP; Department of Microbiology and Immunology, Indiana University School of Medicine, Indianapolis, IN, United States of America.
Post DM; Buck Institute for Research on Aging, Novato, CA, United States of America.
Rinker SD; Department of Microbiology and Immunology, Indiana University School of Medicine, Indianapolis, IN, United States of America.
Reinders LM; Buck Institute for Research on Aging, Novato, CA, United States of America.
Fortney KR; Department of Microbiology and Immunology, Indiana University School of Medicine, Indianapolis, IN, United States of America.
Zwickl BW; Department of Medicine, Indiana University School of Medicine, Indianapolis, IN, United States of America.
Janowicz DM; Department of Medicine, Indiana University School of Medicine, Indianapolis, IN, United States of America.
Baye FM; Department of Biostatistics, Indiana University School of Medicine, Indianapolis, IN, United States of America; Department of Biostatistics, Richard M. Fairbanks School of Public Health, Indianapolis, IN, United States of America.
Katz BP; Department of Biostatistics, Indiana University School of Medicine, Indianapolis, IN, United States of America; Department of Biostatistics, Richard M. Fairbanks School of Public Health, Indianapolis, IN, United States of America.
Spinola SM; Department of Microbiology and Immunology, Indiana University School of Medicine, Indianapolis, IN, United States of America; Department of Medicine, Indiana University School of Medicine, Indianapolis, IN, United States of America; Department of Pathology and Laboratory Medicine, Indiana University
Bauer ME; Department of Microbiology and Immunology, Indiana University School of Medicine, Indianapolis, IN, United States of America.

PLoS One ; 10(4): e0124373, 2015.

Article en En | MEDLINE | ID: mdl-25902140

Asunto(s)

Proteínas Bacterianas/genética; Farmacorresistencia Bacteriana/genética; Etanolaminofosfotransferasa/genética; Haemophilus ducreyi/genética; Lípido A/metabolismo; Administración Oral; Adulto; Antibacterianos/uso terapéutico; Péptidos Catiónicos Antimicrobianos/farmacología; Proteínas Bacterianas/metabolismo; Chancroide/tratamiento farmacológico; Chancroide/microbiología; Chancroide/patología; Ciprofloxacina/uso terapéutico; Etanolaminofosfotransferasa/metabolismo; Etanolaminas/metabolismo; Femenino; Eliminación de Gen; Expresión Génica; Prueba de Complementación Genética; Haemophilus ducreyi/efectos de los fármacos; Haemophilus ducreyi/metabolismo; Haemophilus ducreyi/patogenicidad; Voluntarios Sanos; Humanos; Lípido A/química; Masculino; Mutación; Unión Proteica; Electricidad Estática; alfa-Defensinas/farmacología; beta-Defensinas/farmacología; Catelicidinas

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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Proteínas Bacterianas / Haemophilus ducreyi / Farmacorresistencia Bacteriana / Etanolaminofosfotransferasa / Lípido A Límite: Adult / Female / Humans / Male Idioma: En Revista: PLoS One Asunto de la revista: CIENCIA / MEDICINA Año: 2015 Tipo del documento: Article País de afiliación: Estados Unidos Pais de publicación: Estados Unidos

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