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Rhinovirus is an important pathogen in upper and lower respiratory tract infections in Mexican children.
Aponte, Fernando E; Taboada, Blanca; Espinoza, Marco A; Arias-Ortiz, María A; Monge-Martínez, Jesús; Rodríguez-Vázquez, Rubén; Díaz-Hernández, Fidel; Zárate-Vidal, Fernando; Wong-Chew, Rosa María; Firo-Reyes, Verónica; del Río-Almendárez, Carlos N; Gaitán-Meza, Jesús; Villaseñor-Sierra, Alberto; Martínez-Aguilar, Gerardo; García-Borjas, Maricela; Noyola, Daniel E; Pérez-Gónzalez, Luis F; López, Susana; Santos-Preciado, José I; Arias, Carlos F.
Afiliación
  • Aponte FE; Instituto de Biotecnología, Universidad Nacional Autónoma de México, Av.Universidad 2001, Colonia Chamilpa, Cuernavaca, Morelos, 62210, Mexico. asef@ibt.unam.mx.
  • Taboada B; Instituto de Biotecnología, Universidad Nacional Autónoma de México, Av.Universidad 2001, Colonia Chamilpa, Cuernavaca, Morelos, 62210, Mexico. btaboada@ibt.unam.mx.
  • Espinoza MA; Instituto de Biotecnología, Universidad Nacional Autónoma de México, Av.Universidad 2001, Colonia Chamilpa, Cuernavaca, Morelos, 62210, Mexico. maet@ibt.unam.mx.
  • Arias-Ortiz MA; Colegio de Pediatría del Estado de Veracruz, Veracruz, Mexico. dra_maryarias@hotmail.com.
  • Monge-Martínez J; Colegio de Pediatría del Estado de Veracruz, Veracruz, Mexico. monge_jesus@hotmail.com.
  • Rodríguez-Vázquez R; Colegio de Pediatría del Estado de Veracruz, Veracruz, Mexico. dr_pediatri@hotmail.com.
  • Díaz-Hernández F; Colegio de Pediatría del Estado de Veracruz, Veracruz, Mexico. fideldh@gmail.com.
  • Zárate-Vidal F; Colegio de Pediatría del Estado de Veracruz, Veracruz, Mexico. fmzv77@hotmail.com.
  • Wong-Chew RM; Facultad de Medicina, Universidad Nacional Autónoma de México, México, D F, Mexico. rmwong@unam.mx.
  • Firo-Reyes V; Hospital General de México, México, D F, Mexico. veronicafr@hotmail.com.
  • del Río-Almendárez CN; Hospital Pediátirco de Coyoacán, México, D F, Mexico. riac06@gmail.com.
  • Gaitán-Meza J; Nuevo Hospital Civil de Guadalajara "Dr. Juan I. Menchaca", Guadalajara, Jalisco, Mexico. jesusgaitan53@hotmail.com.
  • Villaseñor-Sierra A; Centro de Investigación Biomédica de Occidente, IMSS, Guadalajara, Jalisco, Mexico. avillase@prodigy.net.mx.
  • Martínez-Aguilar G; Hospital General de Durango, Durango, Mexico. uimec@yahoo.es.
  • García-Borjas M; Hospital General de Durango, Durango, Mexico. maricela_garcia2010@hotmail.com.
  • Noyola DE; Universidad Autónoma de San Luis Potosí, San Luis Potosí, Mexico. dnoyola@uaslp.mx.
  • Pérez-Gónzalez LF; Hospital Central "Dr. Ignacio Morones Prieto", San Luis Potosí, Mexico. luisfer.luisfernando@gmail.com.
  • López S; Instituto de Biotecnología, Universidad Nacional Autónoma de México, Av.Universidad 2001, Colonia Chamilpa, Cuernavaca, Morelos, 62210, Mexico. susana@ibt.unam.mx.
  • Santos-Preciado JI; Facultad de Medicina, Universidad Nacional Autónoma de México, México, D F, Mexico. joseignaciosantos56@gmail.com.
  • Arias CF; Instituto de Biotecnología, Universidad Nacional Autónoma de México, Av.Universidad 2001, Colonia Chamilpa, Cuernavaca, Morelos, 62210, Mexico. arias@ibt.unam.mx.
Virol J ; 12: 31, 2015 Feb 26.
Article en En | MEDLINE | ID: mdl-25889995
BACKGROUND: Most of the studies characterizing the incidence of rhinovirus (RV) have been carried out in hospitalized children and in developed countries. In those studies, RV-C has been associated with more severe respiratory tract infections than RV species A and B. In this study we determined the frequency and diversity of RV strains associated with upper and lower respiratory tract infections (URTI, LRTI) in Mexico, and describe the clinical characteristics of the illness associated with different RV species. METHODS: A prospective surveillance of 526 and 250 children with URTI and LRTI was carried out. Respiratory samples were analyzed by RT-PCR for viruses. The 5' untranslated region of the RV genome was amplified and sequenced. RESULTS: In the case of URTI, 17.5% were positive for RV, while this virus was found in 24.8% of LRTI. The RV species was determined in 73 children with URTI: 61.6% were RV-A, 37% RV-C and, 1.4% RV-B; and in 43 children with LRTI: 51.2% were RV-A, 41.8% RV-C, and 7% RV-B. No significant differences in clinical characteristics were found in patients with RV-A or RV-C infections. A high genetic diversity of RV strains was found in both URTI and LRTI. CONCLUSIONS: Both RV-A and RV-C species were frequently found in hospitalized as well as in outpatient children. This study underlines the high prevalence and genetic diversity of RV strains in Mexico and the potential severity of disease associated with RV-A and RV-C infections.
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Infecciones del Sistema Respiratorio / Rhinovirus / Infecciones por Picornaviridae Tipo de estudio: Observational_studies / Risk_factors_studies Límite: Child / Child, preschool / Female / Humans / Infant / Male País/Región como asunto: Mexico Idioma: En Revista: Virol J Asunto de la revista: VIROLOGIA Año: 2015 Tipo del documento: Article País de afiliación: México Pais de publicación: Reino Unido
Texto completo
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Infecciones del Sistema Respiratorio / Rhinovirus / Infecciones por Picornaviridae Tipo de estudio: Observational_studies / Risk_factors_studies Límite: Child / Child, preschool / Female / Humans / Infant / Male País/Región como asunto: Mexico Idioma: En Revista: Virol J Asunto de la revista: VIROLOGIA Año: 2015 Tipo del documento: Article País de afiliación: México Pais de publicación: Reino Unido