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Application of Parallel Multiparametric Cell-Based FLIPR Detection Assays for the Identification of Modulators of the Muscarinic Acetylcholine Receptor 4 (M4).
Smith, Emery; Chase, Peter; Niswender, Colleen M; Utley, Thomas J; Sheffler, Douglas J; Noetzel, Meredith J; Lamsal, Atin; Wood, Michael R; Conn, P Jeffrey; Lindsley, Craig W; Madoux, Franck; Acosta, Mary; Scampavia, Louis; Spicer, Timothy; Hodder, Peter.
Afiliación
  • Smith E; The Scripps Research Institute Molecular Screening Center, Scripps Florida, Jupiter, FL, USA.
  • Chase P; The Scripps Research Institute Molecular Screening Center, Scripps Florida, Jupiter, FL, USA.
  • Niswender CM; Department of Pharmacology, Vanderbilt Center for Neuroscience Drug Discovery, Vanderbilt Medical Center, Nashville, TN, USA.
  • Utley TJ; Department of Pharmacology, Vanderbilt Center for Neuroscience Drug Discovery, Vanderbilt Medical Center, Nashville, TN, USA.
  • Sheffler DJ; Department of Pharmacology, Vanderbilt Center for Neuroscience Drug Discovery, Vanderbilt Medical Center, Nashville, TN, USA Cell Death and Survival Networks Research Program, Sanford-Burnham Medical Research Institute, La Jolla, CA, USA.
  • Noetzel MJ; Department of Pharmacology, Vanderbilt Center for Neuroscience Drug Discovery, Vanderbilt Medical Center, Nashville, TN, USA.
  • Lamsal A; Department of Pharmacology, Vanderbilt Center for Neuroscience Drug Discovery, Vanderbilt Medical Center, Nashville, TN, USA.
  • Wood MR; Department of Pharmacology, Vanderbilt Center for Neuroscience Drug Discovery, Vanderbilt Medical Center, Nashville, TN, USA.
  • Conn PJ; Department of Pharmacology, Vanderbilt Center for Neuroscience Drug Discovery, Vanderbilt Medical Center, Nashville, TN, USA.
  • Lindsley CW; Department of Pharmacology, Vanderbilt Center for Neuroscience Drug Discovery, Vanderbilt Medical Center, Nashville, TN, USA.
  • Madoux F; The Scripps Research Institute Molecular Screening Center, Scripps Florida, Jupiter, FL, USA.
  • Acosta M; The Scripps Research Institute Molecular Screening Center, Scripps Florida, Jupiter, FL, USA.
  • Scampavia L; The Scripps Research Institute Molecular Screening Center, Scripps Florida, Jupiter, FL, USA.
  • Spicer T; The Scripps Research Institute Molecular Screening Center, Scripps Florida, Jupiter, FL, USA spicert@scripps.edu.
  • Hodder P; The Scripps Research Institute Molecular Screening Center, Scripps Florida, Jupiter, FL, USA Amgen Inc., Thousand Oaks, CA, USA.
J Biomol Screen ; 20(7): 858-68, 2015 Aug.
Article en En | MEDLINE | ID: mdl-25877150
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Antagonistas Muscarínicos / Agonistas Muscarínicos / Receptor Muscarínico M4 / Descubrimiento de Drogas / Ensayos Analíticos de Alto Rendimiento Tipo de estudio: Diagnostic_studies Límite: Animals / Humans Idioma: En Revista: J Biomol Screen Asunto de la revista: BIOLOGIA MOLECULAR Año: 2015 Tipo del documento: Article País de afiliación: Estados Unidos Pais de publicación: Estados Unidos
Texto completo
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Antagonistas Muscarínicos / Agonistas Muscarínicos / Receptor Muscarínico M4 / Descubrimiento de Drogas / Ensayos Analíticos de Alto Rendimiento Tipo de estudio: Diagnostic_studies Límite: Animals / Humans Idioma: En Revista: J Biomol Screen Asunto de la revista: BIOLOGIA MOLECULAR Año: 2015 Tipo del documento: Article País de afiliación: Estados Unidos Pais de publicación: Estados Unidos