Synthesis of silver nanoparticle and its application.

Pandian, A Muthu Kumara; Karthikeyan, C; Rajasimman, M; Dinesh, M G

Pandian, A Muthu Kumara; Karthikeyan, C; Rajasimman, M; Dinesh, M G.

Afiliación

Pandian AM; Environmental Engineering Laboratory, Department of Chemical Engineering, Annamalai University, Annamalai Nagar, Tamil Nadu, India. Electronic address: mkp.asokan@gmail.com.
Karthikeyan C; Environmental Engineering Laboratory, Department of Chemical Engineering, Annamalai University, Annamalai Nagar, Tamil Nadu, India.
Rajasimman M; Environmental Engineering Laboratory, Department of Chemical Engineering, Annamalai University, Annamalai Nagar, Tamil Nadu, India.
Dinesh MG; Department of Ayurvedic and Siddha medicine, Sriramachandra Medical College, Chennai, Tamil Nadu, India.

Ecotoxicol Environ Saf ; 121: 211-7, 2015 Nov.

Article en En | MEDLINE | ID: mdl-25866204

RESUMEN

In this work, silver nanoparticles have been synthesized by wet chemical technique, green synthesis and microbial methods. Silver nitrate (10(-3)M) was used with aqueous extract to produce silver nanoparticles. From the results it was observed that the yield of nanoparticles was high in green synthesis. The size of the silver nanoparticles was determined from Scanning Electron Microscope analysis (SEM). Fourier Transform Infrared spectroscopy (FTIR) was carried out to determine the presence of biomolecules in them. Its cytotoxic effect was studied in cancerous cell line and normal cell line. MTT assay was done to test its optimal concentration and efficacy which gives valuable information for the use of silver nanoparticles for future cancer therapy.

Asunto(s)

Nanopartículas del Metal/química; Nanotecnología/métodos; Plata/química; Apoptosis/efectos de los fármacos; Supervivencia Celular/efectos de los fármacos; Relación Dosis-Respuesta a Droga; Ajo/química; Células Hep G2; Humanos; Microscopía Electrónica de Rastreo; Tamaño de la Partícula; Extractos Vegetales/farmacología; Hojas de la Planta/química; Plata/metabolismo; Plata/farmacología; Nitrato de Plata/química; Espectrofotometría Ultravioleta; Espectroscopía Infrarroja por Transformada de Fourier; Propiedades de Superficie

Palabras clave

Aillum sativum; Cytotoxicity; Green synthesis; Nanotechnology

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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Plata / Nanotecnología / Nanopartículas del Metal Límite: Humans Idioma: En Revista: Ecotoxicol Environ Saf Año: 2015 Tipo del documento: Article Pais de publicación: Países Bajos

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