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Discovery of a Small-Molecule Probe for V-ATPase Function.
Aldrich, Leslie N; Kuo, Szu-Yu; Castoreno, Adam B; Goel, Gautam; Kuballa, Petric; Rees, Matthew G; Seashore-Ludlow, Brinton A; Cheah, Jaime H; Latorre, Isabel J; Schreiber, Stuart L; Shamji, Alykhan F; Xavier, Ramnik J.
Afiliación
  • Aldrich LN; †Department of Chemistry and Chemical Biology, Harvard University, 12 Oxford Street, Cambridge, Massachusetts 02138, United States.
  • Kuo SY; ‡Center for the Science of Therapeutics, Broad Institute, 415 Main Street, Cambridge, Massachusetts 02142, United States.
  • Castoreno AB; ‡Center for the Science of Therapeutics, Broad Institute, 415 Main Street, Cambridge, Massachusetts 02142, United States.
  • Goel G; §Department of Molecular and Cellular Biology, Harvard University, 52 Oxford Street, Cambridge, Massachusetts 02138, United States.
  • Kuballa P; ‡Center for the Science of Therapeutics, Broad Institute, 415 Main Street, Cambridge, Massachusetts 02142, United States.
  • Rees MG; ∥Center for Computational and Integrative Biology, Massachusetts General Hospital, 185 Cambridge Street, Boston, Massachusetts 02114, United States.
  • Seashore-Ludlow BA; ⊥Center for the Study of Inflammatory Bowel Disease, Massachusetts General Hospital, 55 Fruit Street, Boston, Massachusetts 02114, United States.
  • Cheah JH; #Program in Medical and Population Genetics, Broad Institute, 415 Main Street, Cambridge, Massachusetts 02142, United States.
  • Latorre IJ; ∥Center for Computational and Integrative Biology, Massachusetts General Hospital, 185 Cambridge Street, Boston, Massachusetts 02114, United States.
  • Schreiber SL; ⊥Center for the Study of Inflammatory Bowel Disease, Massachusetts General Hospital, 55 Fruit Street, Boston, Massachusetts 02114, United States.
  • Shamji AF; #Program in Medical and Population Genetics, Broad Institute, 415 Main Street, Cambridge, Massachusetts 02142, United States.
  • Xavier RJ; ‡Center for the Science of Therapeutics, Broad Institute, 415 Main Street, Cambridge, Massachusetts 02142, United States.
J Am Chem Soc ; 137(16): 5563-8, 2015 Apr 29.
Article en En | MEDLINE | ID: mdl-25860544
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: ATPasas de Translocación de Protón Vacuolares / Inhibidores Enzimáticos / Bibliotecas de Moléculas Pequeñas / Lisosomas Límite: Humans Idioma: En Revista: J Am Chem Soc Año: 2015 Tipo del documento: Article País de afiliación: Estados Unidos Pais de publicación: Estados Unidos
Texto completo
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: ATPasas de Translocación de Protón Vacuolares / Inhibidores Enzimáticos / Bibliotecas de Moléculas Pequeñas / Lisosomas Límite: Humans Idioma: En Revista: J Am Chem Soc Año: 2015 Tipo del documento: Article País de afiliación: Estados Unidos Pais de publicación: Estados Unidos