Cholesterol anchored arabinogalactan for asialoglycoprotein receptor targeting: synthesis, characterization, and proof of concept of hepatospecific delivery.

Pathak, Pankaj Omprakash; Nagarsenker, Mangal Shailesh; Barhate, Chandrashekhar Rishikant; Padhye, Sameer Govind; Dhawan, Vivek Vijay; Bhattacharyya, Dibyendu; Viswanathan, C L; Steiniger, Frank; Fahr, Alfred

Pathak, Pankaj Omprakash; Nagarsenker, Mangal Shailesh; Barhate, Chandrashekhar Rishikant; Padhye, Sameer Govind; Dhawan, Vivek Vijay; Bhattacharyya, Dibyendu; Viswanathan, C L; Steiniger, Frank; Fahr, Alfred.

Afiliación

Pathak PO; Department of Pharmaceutics, Bombay College of Pharmacy, Kalina, Mumbai 400098, Maharashtra, India.
Nagarsenker MS; Department of Pharmaceutics, Bombay College of Pharmacy, Kalina, Mumbai 400098, Maharashtra, India. Electronic address: mangal.nagarsenker@gmail.com.
Barhate CR; Department of Pharmaceutical Chemistry, Bombay College of Pharmacy, Kalina, Mumbai 400098, Maharashtra, India.
Padhye SG; Department of Pharmaceutics, Bombay College of Pharmacy, Kalina, Mumbai 400098, Maharashtra, India.
Dhawan VV; Department of Pharmaceutics, Bombay College of Pharmacy, Kalina, Mumbai 400098, Maharashtra, India.
Bhattacharyya D; Tata Memorial Centre, Advanced Centre for Treatment Research & Education in Cancer (ACTREC), Kharghar, Navi Mumbai, Maharashtra, India.
Viswanathan CL; Sterling Institute of Pharmacy, Navi Mumbai, Maharashtra, India.
Steiniger F; Department of Pharmaceutical Technology, Friedrich-Schiller-University Jena, Lessing-str. 8, D-07743 Jena, Germany.
Fahr A; Department of Pharmaceutical Technology, Friedrich-Schiller-University Jena, Lessing-str. 8, D-07743 Jena, Germany.

Carbohydr Res ; 408: 33-43, 2015 May 18.

Article en En | MEDLINE | ID: mdl-25841057

Asunto(s)

Receptor de Asialoglicoproteína/metabolismo; Colesterol/química; Galactanos/síntesis química; Galactanos/farmacocinética; Liposomas/administración & dosificación; Hígado/metabolismo; Animales; Portadores de Fármacos; Galactanos/química; Células Hep G2; Humanos; Liposomas/efectos adversos; Liposomas/química; Liposomas/farmacocinética; Ratones; Estructura Molecular; Especificidad de Órganos; Tamaño de la Partícula

Palabras clave

ASGPR; Arabinogalactan; Cholesterol; Liposome; Liver targeting

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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Colesterol / Receptor de Asialoglicoproteína / Galactanos / Liposomas / Hígado Límite: Animals / Humans Idioma: En Revista: Carbohydr Res Año: 2015 Tipo del documento: Article País de afiliación: India Pais de publicación: Países Bajos

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