Shiga toxins induce autophagic cell death in intestinal epithelial cells via the endoplasmic reticulum stress pathway.
Autophagy
; 11(2): 344-54, 2015.
Article
en En
| MEDLINE
| ID: mdl-25831014
Palabras clave
3-MA, 3-methyladenine; AO, acridine orange; ATF4, activating transcription factor 4; ATG, autophagy-related; BECN1, Beclin 1, autophagy-related; Baf A1, bafilomycin A1; CASP3, caspase 3, apoptosis-related cysteine peptidase; DDIT3, DNA-damage-inducible transcript 3; E. coli O157:H7; EHEC O157, Escherichia coli O157:H7; ER stress; FACS, fluorescence activated cell sorting; MAP1LC3B, microtubule-associated protein 1 light chain 3 beta; MAPK, mitogen-activated protein kinase; MDC, monodansylcadaverine; NUPR1, nuclear protein, transcriptional regulator, 1; PARP1, poly (ADP-ribose) polymerase 1; PBS, phosphate-buffered saline; PI, propidium iodide; Shiga toxins; Stxs, Shiga toxins; TEM, transmission electron microscopy; TRIB3, tribbles pseudokinase 3; Thap, thapsigargin; WT, wild type; Z-VAD, Z-VAD-FMK; autophagic cell death; autophagy; Δ, knockout
Texto completo:
1
Colección:
01-internacional
Base de datos:
MEDLINE
Asunto principal:
Autofagia
/
Apoptosis
/
Toxinas Shiga
/
Células Epiteliales
/
Estrés del Retículo Endoplásmico
Tipo de estudio:
Prognostic_studies
Límite:
Animals
/
Humans
Idioma:
En
Revista:
Autophagy
Año:
2015
Tipo del documento:
Article
País de afiliación:
China
Pais de publicación:
Estados Unidos