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A Nurr1 agonist causes neuroprotection in a Parkinson's disease lesion model primed with the toll-like receptor 3 dsRNA inflammatory stimulant poly(I:C).
Smith, Gaynor A; Rocha, Emily M; Rooney, Thomas; Barneoud, Pascal; McLean, Jesse R; Beagan, Jonathan; Osborn, Teresia; Coimbra, Madeleine; Luo, Yongyi; Hallett, Penelope J; Isacson, Ole.
Afiliación
  • Smith GA; Neuroregeneration Research Institute, Harvard Medical School/McLean Hospital, Belmont, Massachusetts, United States of America.
  • Rocha EM; Neuroregeneration Research Institute, Harvard Medical School/McLean Hospital, Belmont, Massachusetts, United States of America.
  • Rooney T; Sanofi, Neurodegeneration and Pain Unit, Chilly-Mazarin, France.
  • Barneoud P; Sanofi, Neurodegeneration and Pain Unit, Chilly-Mazarin, France.
  • McLean JR; Neuroregeneration Research Institute, Harvard Medical School/McLean Hospital, Belmont, Massachusetts, United States of America.
  • Beagan J; Neuroregeneration Research Institute, Harvard Medical School/McLean Hospital, Belmont, Massachusetts, United States of America.
  • Osborn T; Neuroregeneration Research Institute, Harvard Medical School/McLean Hospital, Belmont, Massachusetts, United States of America.
  • Coimbra M; Sanofi, Disposition, Safety & Animal Research, Department 1, Chilly-Mazarin, France.
  • Luo Y; Sanofi-Genzyme, Drug Metabolism and Pharmacokinetics Department, Waltham, Massachusetts, United States of America.
  • Hallett PJ; Neuroregeneration Research Institute, Harvard Medical School/McLean Hospital, Belmont, Massachusetts, United States of America.
  • Isacson O; Neuroregeneration Research Institute, Harvard Medical School/McLean Hospital, Belmont, Massachusetts, United States of America.
PLoS One ; 10(3): e0121072, 2015.
Article en En | MEDLINE | ID: mdl-25815475
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Enfermedad de Parkinson Secundaria / Piridinas / Dopamina / Receptor Toll-Like 3 / Miembro 2 del Grupo A de la Subfamilia 4 de Receptores Nucleares / Imidazoles / Inflamación Tipo de estudio: Etiology_studies / Prognostic_studies Límite: Animals Idioma: En Revista: PLoS One Asunto de la revista: CIENCIA / MEDICINA Año: 2015 Tipo del documento: Article País de afiliación: Estados Unidos Pais de publicación: Estados Unidos
Texto completo
Añadir a Mi BVS
Imprimir
XML
PubMed Links
Buscar en Google

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Enfermedad de Parkinson Secundaria / Piridinas / Dopamina / Receptor Toll-Like 3 / Miembro 2 del Grupo A de la Subfamilia 4 de Receptores Nucleares / Imidazoles / Inflamación Tipo de estudio: Etiology_studies / Prognostic_studies Límite: Animals Idioma: En Revista: PLoS One Asunto de la revista: CIENCIA / MEDICINA Año: 2015 Tipo del documento: Article País de afiliación: Estados Unidos Pais de publicación: Estados Unidos