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HDL particle subpopulations: Focus on biological function.
Rached, Fabiana H; Chapman, M John; Kontush, Anatol.
Afiliación
  • Rached FH; National Institute for Health and Medical Research (INSERM), UMR-ICAN 1166, Université Pierre et Marie Curie-Paris 6, AP-HP, Pitié-Salpétrière University Hospital, ICAN, Paris, France; Heart Institute-InCor, University of Sao Paulo Medical School Hospital, Sao Paulo, Brazil; Hospital Israelita Albert Einstein, Sao Paulo, Brazil.
Biofactors ; 41(2): 67-77, 2015.
Article en En | MEDLINE | ID: mdl-25809447
Low levels of high-density lipoprotein-cholesterol (HDL-C) constitute an independent biomarker of cardiovascular morbi-mortality. However, recent advances have drastically modified the classical and limited view of HDL as a carrier of 'good cholesterol', and have revealed unexpected levels of complexity in the circulating HDL particle pool. HDL particles are indeed highly heterogeneous in structure, intravascular metabolism and biological activity. This review describes recent progress in our understanding of HDL subpopulations and their biological activities, and focuses on relationships between the structural, compositional and functional heterogeneity of HDL particles.
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Vasodilatadores / Enfermedades Cardiovasculares / Antiinflamatorios no Esteroideos / Fibrinolíticos / HDL-Colesterol / Antioxidantes Límite: Animals / Humans Idioma: En Revista: Biofactors Asunto de la revista: BIOQUIMICA Año: 2015 Tipo del documento: Article País de afiliación: Brasil Pais de publicación: Países Bajos

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Vasodilatadores / Enfermedades Cardiovasculares / Antiinflamatorios no Esteroideos / Fibrinolíticos / HDL-Colesterol / Antioxidantes Límite: Animals / Humans Idioma: En Revista: Biofactors Asunto de la revista: BIOQUIMICA Año: 2015 Tipo del documento: Article País de afiliación: Brasil Pais de publicación: Países Bajos