Inhibition of Zn(II) binding type IA topoisomerases by organomercury compounds and Hg(II).

Cheng, Bokun; Annamalai, Thirunavukkarasu; Sandhaus, Shayna; Bansod, Priyanka; Tse-Dinh, Yuk-Ching

Cheng, Bokun; Annamalai, Thirunavukkarasu; Sandhaus, Shayna; Bansod, Priyanka; Tse-Dinh, Yuk-Ching.

Afiliación

Cheng B; Department of Biochemistry and Molecular Biology, New York Medical College, Valhalla, New York, United States of America.
Annamalai T; Department of Chemistry and Biochemistry, Florida International University, Miami, Florida, United States of America.
Sandhaus S; Department of Chemistry and Biochemistry, Florida International University, Miami, Florida, United States of America.
Bansod P; Department of Chemistry and Biochemistry, Florida International University, Miami, Florida, United States of America.
Tse-Dinh YC; Department of Chemistry and Biochemistry, Florida International University, Miami, Florida, United States of America; Biomolecular Sciences Institute, Florida International University, Miami, Florida, United States of America.

PLoS One ; 10(3): e0120022, 2015.

Article en En | MEDLINE | ID: mdl-25798600

Asunto(s)

ADN-Topoisomerasas de Tipo I/metabolismo; Mercurio/farmacología; Compuestos Organomercuriales/farmacología; Inhibidores de Topoisomerasa I/farmacología; Zinc/metabolismo; Cisteína/metabolismo; ADN-Topoisomerasas de Tipo I/química; Bases de Datos Farmacéuticas; Evaluación Preclínica de Medicamentos; Humanos; Unión Proteica

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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Compuestos Organomercuriales / Zinc / ADN-Topoisomerasas de Tipo I / Inhibidores de Topoisomerasa I / Mercurio Límite: Humans Idioma: En Revista: PLoS One Asunto de la revista: CIENCIA / MEDICINA Año: 2015 Tipo del documento: Article País de afiliación: Estados Unidos Pais de publicación: Estados Unidos

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