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Calcinosis cutis presenting in the context of long-term therapy for chronic myeloid leukemia: a case report and review of the literature.
Altman, Igor; Lee, Ina H; Burns, Matthew R; Rondelli, Damiano; Ennis, William J.
Afiliación
  • Altman I; Department of Surgery, Division of Vascular Surgery, Section of Wound Healing and Tissue Repair, College of Medicine, University of Illinois Hospital and Health Sciences System, Chicago, IL; email: ialtman@uic.edu.
  • Lee IH; Department of Surgery, Division of Vascular Surgery, Section of Wound Healing and Tissue Repair, College of Medicine, University of Illinois Hospital and Health Sciences System, Chicago, IL.
  • Burns MR; Department of Surgery, Division of Vascular Surgery, Section of Wound Healing and Tissue Repair, College of Medicine, University of Illinois Hospital and Health Sciences System, Chicago, IL.
  • Rondelli D; Department of Surgery, Division of Vascular Surgery, Section of Wound Healing and Tissue Repair, College of Medicine, University of Illinois Hospital and Health Sciences System, Chicago, IL.
  • Ennis WJ; Department of Surgery, Division of Vascular Surgery, Section of Wound Healing and Tissue Repair, College of Medicine, University of Illinois Hospital and Health Sciences System, Chicago, IL.
Wounds ; 27(2): 20-5, 2015 Feb.
Article en En | MEDLINE | ID: mdl-25785904
Calcinosis cutis is a poorly understood process in which calcium salts deposit in the skin and subcutaneous tissues. Due to its multifactorial pathogenesis, several subtypes and potential etiologies have been described. Presented here is a case of bilateral pretibial calcinosis cutis in a patient on long-term tyrosine kinase inhibitor therapy for chronic myeloid leukemia. The patient initially presented with a right tibial ulceration treated with multiple surgical debridements, antibiotics, and negative pressure wound therapy. The wound was ultimately closed with a split-thickness skin graft. Relevant literature is examined and several possible mechanisms are discussed.
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Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Piel / Cicatrización de Heridas / Calcinosis / Leucemia Mielógena Crónica BCR-ABL Positiva / Trasplante de Piel / Desbridamiento / Úlcera de la Pierna Límite: Humans / Male / Middle aged Idioma: En Revista: Wounds Año: 2015 Tipo del documento: Article Pais de publicación: Estados Unidos
Buscar en Google
Añadir a Mi BVS
Imprimir
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PubMed Links

Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Piel / Cicatrización de Heridas / Calcinosis / Leucemia Mielógena Crónica BCR-ABL Positiva / Trasplante de Piel / Desbridamiento / Úlcera de la Pierna Límite: Humans / Male / Middle aged Idioma: En Revista: Wounds Año: 2015 Tipo del documento: Article Pais de publicación: Estados Unidos