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In this correspondence, preliminary data in 100 lithium users found that urine osmolality correlated with chronic kidney disease, diabetes mellitus, and hypothyroidism. We hypothesize that GSK-3ß inhibition is a potential mechanism for lithium-associated medical illness.
Rej, Soham; Segal, Marilyn; Low, Nancy C P; Mucsi, Istvan; Holcroft, Christina; Shulman, Kenneth; Looper, Karl J.
Afiliación
  • Rej S; Department of Psychiatry, McGill University, Montreal, QC, Canada; Division of Geriatric Psychiatry, Department of Psychiatry, Sunnybrook Health Sciences Centre, University of Toronto, Toronto, ON, Canada. Electronic address: soham.rej@mail.mcgill.ca.
  • Segal M; Department of Psychiatry, McGill University, Montreal, QC, Canada.
  • Low NC; Department of Psychiatry, McGill University, Montreal, QC, Canada.
  • Mucsi I; Division of Nephrology, Department of Medicine, University Health Network (UHN), University of Toronto, Toronto, ON, Canada.
  • Holcroft C; Biostatistician, Boston, MA, USA.
  • Shulman K; Division of Geriatric Psychiatry, Department of Psychiatry, Sunnybrook Health Sciences Centre, University of Toronto, Toronto, ON, Canada.
  • Looper KJ; Department of Psychiatry, McGill University, Montreal, QC, Canada.
Med Hypotheses ; 84(6): 602, 2015 Jun.
Article en En | MEDLINE | ID: mdl-25777472
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Trastornos del Humor / Glucógeno Sintasa Quinasa 3 / Diabetes Mellitus / Insuficiencia Renal Crónica / Hipotiroidismo / Litio Tipo de estudio: Risk_factors_studies Límite: Adult / Aged / Aged80 / Female / Humans / Male / Middle aged Idioma: En Revista: Med Hypotheses Año: 2015 Tipo del documento: Article Pais de publicación: Estados Unidos
Texto completo
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XML
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Trastornos del Humor / Glucógeno Sintasa Quinasa 3 / Diabetes Mellitus / Insuficiencia Renal Crónica / Hipotiroidismo / Litio Tipo de estudio: Risk_factors_studies Límite: Adult / Aged / Aged80 / Female / Humans / Male / Middle aged Idioma: En Revista: Med Hypotheses Año: 2015 Tipo del documento: Article Pais de publicación: Estados Unidos