Reinterpreting the best biomarker of oxidative stress: The 8-iso-PGF(2&#945;)/PGF(2&#945;) ratio distinguishes chemical from enzymatic lipid peroxidation.

van 't Erve, Thomas J; Lih, Fred B; Kadiiska, Maria B; Deterding, Leesa J; Eling, Thomas E; Mason, Ronald P

Reinterpreting the best biomarker of oxidative stress: The 8-iso-PGF(2α)/PGF(2α) ratio distinguishes chemical from enzymatic lipid peroxidation.

van 't Erve, Thomas J; Lih, Fred B; Kadiiska, Maria B; Deterding, Leesa J; Eling, Thomas E; Mason, Ronald P.

Afiliación

van 't Erve TJ; Immunity, Inflammation and Disease Laboratory, National Institute of Environmental Health Sciences, Research Triangle Park, NC 27709, USA. Electronic address: thomas.vanterve@nih.gov.
Lih FB; Epigenetic and Stem Cell Biology Laboratory, National Institute of Environmental Health Sciences, Research Triangle Park, NC 27709, USA.
Kadiiska MB; Immunity, Inflammation and Disease Laboratory, National Institute of Environmental Health Sciences, Research Triangle Park, NC 27709, USA.
Deterding LJ; Epigenetic and Stem Cell Biology Laboratory, National Institute of Environmental Health Sciences, Research Triangle Park, NC 27709, USA.
Eling TE; Emeritus, National Institute of Environmental Health Sciences, Research Triangle Park, NC 27709, USA.
Mason RP; Immunity, Inflammation and Disease Laboratory, National Institute of Environmental Health Sciences, Research Triangle Park, NC 27709, USA.

Free Radic Biol Med ; 83: 245-51, 2015 Jun.

Article en En | MEDLINE | ID: mdl-25772010

Asunto(s)

Biomarcadores/metabolismo; Dinoprost/análogos & derivados; Dinoprost/metabolismo; Inflamación/diagnóstico; Peroxidación de Lípido; Estrés Oxidativo; Prostaglandina-Endoperóxido Sintasas/metabolismo; Adulto; Animales; Cromatografía Liquida; Inhibidores Enzimáticos/farmacología; Humanos; Inflamación/metabolismo; Masculino; Prostaglandina-Endoperóxido Sintasas/química; Ratas; Ratas Endogámicas F344; Espectrometría de Masas en Tándem

Palabras clave

Biomarkers; F(2)-isoprostanes; Inflammation; Lipid peroxidation; Oxidative stress

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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Biomarcadores / Dinoprost / Peroxidación de Lípido / Prostaglandina-Endoperóxido Sintasas / Estrés Oxidativo / Inflamación Tipo de estudio: Prognostic_studies Límite: Adult / Animals / Humans / Male Idioma: En Revista: Free Radic Biol Med Asunto de la revista: BIOQUIMICA / MEDICINA Año: 2015 Tipo del documento: Article Pais de publicación: Estados Unidos

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