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The cell biology of fat expansion.
Rutkowski, Joseph M; Stern, Jennifer H; Scherer, Philipp E.
Afiliación
  • Rutkowski JM; Touchstone Diabetes Center, Department of Internal Medicine, and Department of Cell Biology, University of Texas Southwestern Medical Center, Dallas, TX 75390.
  • Stern JH; Touchstone Diabetes Center, Department of Internal Medicine, and Department of Cell Biology, University of Texas Southwestern Medical Center, Dallas, TX 75390.
  • Scherer PE; Touchstone Diabetes Center, Department of Internal Medicine, and Department of Cell Biology, University of Texas Southwestern Medical Center, Dallas, TX 75390 Touchstone Diabetes Center, Department of Internal Medicine, and Department of Cell Biology, University of Texas Southwestern Medical Center, Dallas, TX 75390 philipp.scherer@utsouthwestern.edu.
J Cell Biol ; 208(5): 501-12, 2015 Mar 02.
Article en En | MEDLINE | ID: mdl-25733711
Adipose tissue is a complex, multicellular organ that profoundly influences the function of nearly all other organ systems through its diverse metabolite and adipokine secretome. Adipocytes are the primary cell type of adipose tissue and play a key role in maintaining energy homeostasis. The efficiency with which adipose tissue responds to whole-body energetic demands reflects the ability of adipocytes to adapt to an altered nutrient environment, and has profound systemic implications. Deciphering adipocyte cell biology is an important component of understanding how the aberrant physiology of expanding adipose tissue contributes to the metabolic dysregulation associated with obesity.
Asunto(s)

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Tejido Adiposo / Adipocitos / Metabolismo Energético / Obesidad Límite: Animals / Humans Idioma: En Revista: J Cell Biol Año: 2015 Tipo del documento: Article Pais de publicación: Estados Unidos

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Tejido Adiposo / Adipocitos / Metabolismo Energético / Obesidad Límite: Animals / Humans Idioma: En Revista: J Cell Biol Año: 2015 Tipo del documento: Article Pais de publicación: Estados Unidos