Consistent delayed unilateral neuronal death after modified transient focal cerebral ischemia in mice that mimics neuronal injury after transient global cerebral ischemia.

Nishijima, Yasuo; Niizuma, Kuniyasu; Fujimura, Miki; Akamatsu, Yosuke; Shimizu, Hiroaki; Tominaga, Teiji

Nishijima, Yasuo; Niizuma, Kuniyasu; Fujimura, Miki; Akamatsu, Yosuke; Shimizu, Hiroaki; Tominaga, Teiji.

Afiliación

Nishijima Y; Department of Neurosurgery, Tohoku University Graduate School of Medicine, Sendai, Japan.
Niizuma K; Department of Neurosurgery, Tohoku University Graduate School of Medicine, Sendai, Japan.
Fujimura M; Department of Neurosurgery, Tohoku University Graduate School of Medicine, Sendai, Japan.
Akamatsu Y; Department of Neurosurgery, Tohoku University Graduate School of Medicine, Sendai, Japan.
Shimizu H; Department of Neurosurgery, Tohoku University Graduate School of Medicine, Sendai, Japan.
Tominaga T; Department of Neurosurgery, Tohoku University Graduate School of Medicine, Sendai, Japan.

J Neurosurg ; 123(1): 243-53, 2015 Jul.

Article en En | MEDLINE | ID: mdl-25723306

Asunto(s)

Región CA1 Hipocampal/patología; Modelos Animales de Enfermedad; Ataque Isquémico Transitorio/patología; Neuronas/patología; Animales; Muerte Celular; Circulación Cerebrovascular; Ataque Isquémico Transitorio/etiología; Masculino; Ratones; Ratones Endogámicos C57BL; Procedimientos Neuroquirúrgicos; Suturas/efectos adversos; Factores de Tiempo

Palabras clave

BCCAO = bilateral CCA occlusion; CBF = cerebral blood flow; CCA = common carotid artery; DAB = diaminobenzidine; ECA = external carotid artery; ICA = internal carotid artery; LSF = laser speckle flowmetry; MCA = middle cerebral artery; MCAO = MCA occlusion; PBS = phosphate-buffered saline; PCA = posterior cerebral artery; PCoA = posterior communicating artery; ROI = region of interest; TTC = 2,3,5-triphenyltetrazolium chloride; TUNEL = terminal deoxynucleotidyl transferasemediated deoxyuridine triphosphate nick-end labeling; apoptosis; delayed neuronal death; hippocampus; laser speckle flowmetry; mice; rCBF = regional CBF; tGCI = transient global cerebral ischemia; unilateral

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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Ataque Isquémico Transitorio / Modelos Animales de Enfermedad / Región CA1 Hipocampal / Neuronas Tipo de estudio: Etiology_studies / Prognostic_studies Límite: Animals Idioma: En Revista: J Neurosurg Año: 2015 Tipo del documento: Article País de afiliación: Japón Pais de publicación: Estados Unidos

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