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Oxidized LDL activates blood platelets through CD36/NOX2-mediated inhibition of the cGMP/protein kinase G signaling cascade.
Magwenzi, Simbarashe; Woodward, Casey; Wraith, Katie S; Aburima, Ahmed; Raslan, Zaher; Jones, Huw; McNeil, Catriona; Wheatcroft, Stephen; Yuldasheva, Nadira; Febbriao, Maria; Kearney, Mark; Naseem, Khalid M.
Afiliación
  • Magwenzi S; Centre for Cardiovascular and Metabolic Research, Hull-York Medical School, Thrombosis Research Laboratory (013/014), University of Hull, Hull, United Kingdom;
  • Woodward C; Centre for Cardiovascular and Metabolic Research, Hull-York Medical School, Thrombosis Research Laboratory (013/014), University of Hull, Hull, United Kingdom;
  • Wraith KS; Centre for Cardiovascular and Metabolic Research, Hull-York Medical School, Thrombosis Research Laboratory (013/014), University of Hull, Hull, United Kingdom;
  • Aburima A; Centre for Cardiovascular and Metabolic Research, Hull-York Medical School, Thrombosis Research Laboratory (013/014), University of Hull, Hull, United Kingdom;
  • Raslan Z; Centre for Cardiovascular and Metabolic Research, Hull-York Medical School, Thrombosis Research Laboratory (013/014), University of Hull, Hull, United Kingdom;
  • Jones H; Centre for Cardiovascular and Metabolic Research, Hull-York Medical School, Thrombosis Research Laboratory (013/014), University of Hull, Hull, United Kingdom;
  • McNeil C; Centre for Cardiovascular and Metabolic Research, Hull-York Medical School, Thrombosis Research Laboratory (013/014), University of Hull, Hull, United Kingdom;
  • Wheatcroft S; Division of Cardiovascular and Diabetes Research, Leeds Multidisciplinary Cardiovascular Research Centre, LIGHT Laboratories, University of Leeds, Leeds, United Kingdom; and.
  • Yuldasheva N; Division of Cardiovascular and Diabetes Research, Leeds Multidisciplinary Cardiovascular Research Centre, LIGHT Laboratories, University of Leeds, Leeds, United Kingdom; and.
  • Febbriao M; School of Dentistry, University of Alberta, Edmonton, AB, Canada.
  • Kearney M; Division of Cardiovascular and Diabetes Research, Leeds Multidisciplinary Cardiovascular Research Centre, LIGHT Laboratories, University of Leeds, Leeds, United Kingdom; and.
  • Naseem KM; Centre for Cardiovascular and Metabolic Research, Hull-York Medical School, Thrombosis Research Laboratory (013/014), University of Hull, Hull, United Kingdom;
Blood ; 125(17): 2693-703, 2015 Apr 23.
Article en En | MEDLINE | ID: mdl-25710879
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Plaquetas / Glicoproteínas de Membrana / Transducción de Señal / Proteínas Quinasas Dependientes de GMP Cíclico / Antígenos CD36 / NADPH Oxidasas / Lipoproteínas LDL Límite: Animals / Humans Idioma: En Revista: Blood Año: 2015 Tipo del documento: Article Pais de publicación: Estados Unidos
Texto completo
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Plaquetas / Glicoproteínas de Membrana / Transducción de Señal / Proteínas Quinasas Dependientes de GMP Cíclico / Antígenos CD36 / NADPH Oxidasas / Lipoproteínas LDL Límite: Animals / Humans Idioma: En Revista: Blood Año: 2015 Tipo del documento: Article Pais de publicación: Estados Unidos