Your browser doesn't support javascript.
loading
Sentinel lymph node biopsy is not warranted following a core needle biopsy diagnosis of ductal carcinoma in situ (DCIS) of the breast.
Prendeville, Susan; Ryan, Ciara; Feeley, Linda; O'Connell, Fionnuala; Browne, Tara Jane; O'Sullivan, Martin J; Bennett, Michael W.
Afiliación
  • Prendeville S; Department of Histopathology, Cork University Hospital, Wilton, Cork, Ireland.
  • Ryan C; Department of Histopathology, Cork University Hospital, Wilton, Cork, Ireland.
  • Feeley L; Department of Histopathology, Cork University Hospital, Wilton, Cork, Ireland.
  • O'Connell F; Department of Histopathology, Cork University Hospital, Wilton, Cork, Ireland.
  • Browne TJ; Department of Histopathology, Cork University Hospital, Wilton, Cork, Ireland.
  • O'Sullivan MJ; Department of Surgery, Cork University Hospital, Wilton, Cork, Ireland; BreastCheck Southern Unit (National Cancer Screening Service), Infirmary Road, Cork, Ireland.
  • Bennett MW; Department of Histopathology, Cork University Hospital, Wilton, Cork, Ireland; BreastCheck Southern Unit (National Cancer Screening Service), Infirmary Road, Cork, Ireland. Electronic address: Michael.bennett@hse.ie.
Breast ; 24(3): 197-200, 2015 Jun.
Article en En | MEDLINE | ID: mdl-25681861
INTRODUCTION: The role of sentinel lymph node biopsy (SLNB) in ductal carcinoma in situ (DCIS) is controversial. This study evaluates the risk of clinically relevant SLN metastasis following a core needle biopsy (CNB) diagnosis of pure DCIS. MATERIALS AND METHODS: Cases that underwent SLNB following a CNB diagnosis of pure DCIS at our institution over a 4.5 year period were evaluated. Parameters including the DCIS characteristics on CNB, the rate of upstaging to invasive carcinoma at excision and the SLNB result were recorded. RESULTS: Of 296 patients with a CNB diagnosis DCIS, 181 had SLNB (62%). The rate of invasion at excision in those undergoing SLNB was 30% (54/181). SLN metastasis was detected in 7/181 cases (4%), including 6 cases with isolated tumour cells only (3.5%) and only 1 case with a macro-metastatic deposit (0.5%). CONCLUSION: The risk of clinically significant SLN metastasis following a CNB diagnosis of DCIS is extremely low, despite a relatively high rate of upstaging to invasive carcinoma at excision. Our findings support the opinion that SLNB is not warranted following a CNB diagnosis of DCIS, particularly for those patients undergoing breast conservation surgery.
Asunto(s)
Palabras clave
Texto completo
Añadir a Mi BVS
Imprimir
XML
PubMed Links
Buscar en Google

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Neoplasias de la Mama / Carcinoma Intraductal no Infiltrante / Biopsia del Ganglio Linfático Centinela / Biopsia con Aguja Gruesa Tipo de estudio: Diagnostic_studies / Etiology_studies / Evaluation_studies / Incidence_studies / Observational_studies / Risk_factors_studies Límite: Female / Humans Idioma: En Revista: Breast Asunto de la revista: ENDOCRINOLOGIA / NEOPLASIAS Año: 2015 Tipo del documento: Article País de afiliación: Irlanda Pais de publicación: Países Bajos
Texto completo
Añadir a Mi BVS
Imprimir
XML
PubMed Links
Buscar en Google

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Neoplasias de la Mama / Carcinoma Intraductal no Infiltrante / Biopsia del Ganglio Linfático Centinela / Biopsia con Aguja Gruesa Tipo de estudio: Diagnostic_studies / Etiology_studies / Evaluation_studies / Incidence_studies / Observational_studies / Risk_factors_studies Límite: Female / Humans Idioma: En Revista: Breast Asunto de la revista: ENDOCRINOLOGIA / NEOPLASIAS Año: 2015 Tipo del documento: Article País de afiliación: Irlanda Pais de publicación: Países Bajos