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Belching, regurgitation, chest tightness and dyspnea: not gastroesophageal reflux disease but asthma.
Zhang, Jing-Xi; Zhan, Xian-Bao; Bai, Chong; Li, Qiang.
Afiliación
  • Zhang JX; Jing-Xi Zhang, Chong Bai, Qiang Li, Department of Respiratory diseases, Changhai Hospital, the Second Military Medical University, Shanghai 200433, China.
  • Zhan XB; Jing-Xi Zhang, Chong Bai, Qiang Li, Department of Respiratory diseases, Changhai Hospital, the Second Military Medical University, Shanghai 200433, China.
  • Bai C; Jing-Xi Zhang, Chong Bai, Qiang Li, Department of Respiratory diseases, Changhai Hospital, the Second Military Medical University, Shanghai 200433, China.
  • Li Q; Jing-Xi Zhang, Chong Bai, Qiang Li, Department of Respiratory diseases, Changhai Hospital, the Second Military Medical University, Shanghai 200433, China.
World J Gastroenterol ; 21(5): 1680-3, 2015 Feb 07.
Article en En | MEDLINE | ID: mdl-25663791
Belching is a common symptom of gastroesophageal reflux disease. If the symptoms are not relieved after anti-reflux treatment, another etiology should be considered. Here, we report a case of a 43-year-old man who presented with belching, regurgitation, chest tightness and dyspnea for 18 mo, which became gradually more severe. Gastroscopic examination suggested superficial gastritis. Twenty-four-hour esophageal pH monitoring showed that the Demeester score was 11.4, in the normal range. High-resolution manometry showed that integrated relaxation pressure and intrabolus pressure were higher than normal (20 mmHg and 22.4 mmHg, respectively), indicating gastroesophageal junction outflow tract obstruction. Pulmonary function test showed severe obstructive ventilation dysfunction [forced expiratory volume in 1 second (FEV1)/forced vital capacity 32%, FEV1 was 1.21 L, occupying 35% predicted value after salbuterol inhalation], and positive bronchial dilation test (∆FEV1 260 mL, ∆FEV1% 27%). Skin prick test showed Dermatophagoides farinae (++), house dust mite (++++), and shrimp protein (++). Fractional exhaled nitric oxide measurement was 76 ppb. All the symptoms were alleviated completely and pulmonary function increased after combination therapy with corticosteroids and long-acting ß2-agonist. Bronchial asthma was eventually diagnosed by laboratory tests and the effect of anti-asthmatic treatment, therefore, physicians, especially the Gastrointestinal physicians, should pay attention to the belching symptoms of asthma.
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Asma / Reflujo Gastroesofágico / Disnea / Eructación / Reflujo Laringofaríngeo / Pulmón Tipo de estudio: Diagnostic_studies / Etiology_studies / Prognostic_studies / Risk_factors_studies Límite: Adult / Humans / Male Idioma: En Revista: World J Gastroenterol Asunto de la revista: GASTROENTEROLOGIA Año: 2015 Tipo del documento: Article País de afiliación: China Pais de publicación: Estados Unidos
Texto completo
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Asma / Reflujo Gastroesofágico / Disnea / Eructación / Reflujo Laringofaríngeo / Pulmón Tipo de estudio: Diagnostic_studies / Etiology_studies / Prognostic_studies / Risk_factors_studies Límite: Adult / Humans / Male Idioma: En Revista: World J Gastroenterol Asunto de la revista: GASTROENTEROLOGIA Año: 2015 Tipo del documento: Article País de afiliación: China Pais de publicación: Estados Unidos