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Protosappanin B protects PC12 cells against oxygen-glucose deprivation-induced neuronal death by maintaining mitochondrial homeostasis via induction of ubiquitin-dependent p53 protein degradation.
Zeng, Ke-Wu; Liao, Li-Xi; Zhao, Ming-Bo; Song, Fang-Jiao; Yu, Qian; Jiang, Yong; Tu, Peng-Fei.
Afiliación
  • Zeng KW; State Key Laboratory of Natural and Biomimetic Drugs, School of Pharmaceutical Sciences, Peking University, Beijing 100191, China.
  • Liao LX; State Key Laboratory of Natural and Biomimetic Drugs, School of Pharmaceutical Sciences, Peking University, Beijing 100191, China.
  • Zhao MB; State Key Laboratory of Natural and Biomimetic Drugs, School of Pharmaceutical Sciences, Peking University, Beijing 100191, China.
  • Song FJ; Research Studio of Integration of Traditional and Western Medicine, First Hospital, Peking University, Beijing 100034, China.
  • Yu Q; Research Studio of Integration of Traditional and Western Medicine, First Hospital, Peking University, Beijing 100034, China.
  • Jiang Y; State Key Laboratory of Natural and Biomimetic Drugs, School of Pharmaceutical Sciences, Peking University, Beijing 100191, China.
  • Tu PF; State Key Laboratory of Natural and Biomimetic Drugs, School of Pharmaceutical Sciences, Peking University, Beijing 100191, China. Electronic address: pengfeitu@vip.163.com.
Eur J Pharmacol ; 751: 13-23, 2015 Mar 15.
Article en En | MEDLINE | ID: mdl-25657114
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Oxígeno / Ubiquitinas / Proteína p53 Supresora de Tumor / Oxocinas / Glucosa / Homeostasis / Mitocondrias / Neuronas Límite: Animals Idioma: En Revista: Eur J Pharmacol Año: 2015 Tipo del documento: Article País de afiliación: China Pais de publicación: Países Bajos
Texto completo
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Oxígeno / Ubiquitinas / Proteína p53 Supresora de Tumor / Oxocinas / Glucosa / Homeostasis / Mitocondrias / Neuronas Límite: Animals Idioma: En Revista: Eur J Pharmacol Año: 2015 Tipo del documento: Article País de afiliación: China Pais de publicación: Países Bajos