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Tumor cells chronically treated with a trastuzumab-maytansinoid antibody-drug conjugate develop varied resistance mechanisms but respond to alternate treatments.
Loganzo, Frank; Tan, Xingzhi; Sung, Matthew; Jin, Guixian; Myers, Jeremy S; Melamud, Eugene; Wang, Fang; Diesl, Veronica; Follettie, Maximillian T; Musto, Sylvia; Lam, My-Hanh; Hu, William; Charati, Manoj B; Khandke, Kiran; Kim, Kenny Sung Kyoo; Cinque, Mike; Lucas, Judy; Graziani, Edmund; Maderna, Andreas; O'Donnell, Christopher J; Arndt, Kim T; Gerber, Hans-Peter.
Afiliación
  • Loganzo F; Pfizer Oncology, Pearl River, New York. frank.loganzo@pfizer.com.
  • Tan X; Pfizer Oncology, Pearl River, New York.
  • Sung M; Pfizer Oncology, Pearl River, New York.
  • Jin G; Pfizer Oncology, Pearl River, New York.
  • Myers JS; Pfizer Oncology, Pearl River, New York.
  • Melamud E; Pfizer Oncology, Pearl River, New York.
  • Wang F; Pfizer Oncology, Pearl River, New York.
  • Diesl V; Pfizer Oncology, Andover, Massachusetts.
  • Follettie MT; Pfizer Oncology, Pearl River, New York.
  • Musto S; Pfizer Oncology, Pearl River, New York.
  • Lam MH; Pfizer Oncology, Pearl River, New York.
  • Hu W; Pfizer Oncology, Pearl River, New York.
  • Charati MB; Pfizer Oncology, Pearl River, New York.
  • Khandke K; Pfizer Oncology, Pearl River, New York.
  • Kim KS; Pfizer Oncology, Pearl River, New York.
  • Cinque M; Pfizer Oncology, Pearl River, New York.
  • Lucas J; Pfizer Oncology, Pearl River, New York.
  • Graziani E; Pfizer World Wide Medicinal Chemistry, Groton, Connecticut.
  • Maderna A; Pfizer World Wide Medicinal Chemistry, Groton, Connecticut.
  • O'Donnell CJ; Pfizer World Wide Medicinal Chemistry, Groton, Connecticut.
  • Arndt KT; Pfizer Oncology, Pearl River, New York.
  • Gerber HP; Pfizer Oncology, Pearl River, New York.
Mol Cancer Ther ; 14(4): 952-63, 2015 Apr.
Article en En | MEDLINE | ID: mdl-25646013
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Inmunoconjugados / Resistencia a Antineoplásicos / Trastuzumab / Antineoplásicos Límite: Animals / Female / Humans Idioma: En Revista: Mol Cancer Ther Asunto de la revista: ANTINEOPLASICOS Año: 2015 Tipo del documento: Article Pais de publicación: Estados Unidos
Texto completo
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Inmunoconjugados / Resistencia a Antineoplásicos / Trastuzumab / Antineoplásicos Límite: Animals / Female / Humans Idioma: En Revista: Mol Cancer Ther Asunto de la revista: ANTINEOPLASICOS Año: 2015 Tipo del documento: Article Pais de publicación: Estados Unidos