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2,5-diketopiperazines in food and beverages: Taste and bioactivity.
Borthwick, Alan D; Da Costa, Neil C.
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  • Borthwick AD; a DrugMolDesign , London , United Kingdom.
  • Da Costa NC; b International Flavors & Fragrances, Inc. , Union Beach , New Jersey , USA.
Crit Rev Food Sci Nutr ; 57(4): 718-742, 2017 Mar 04.
Article en En | MEDLINE | ID: mdl-25629623
2,5-Diketopiperazines (2,5-DKPs) have been found to occur in a wide range of food and beverages, and display an array of chemesthetic effects (bitter, astringent, metallic, and umami) that can contribute to the taste of a variety of foods. These smallest cyclic peptides also occur as natural products and have been found to display a variety of bioactivities from antibacterial, antifungal, to anthroprotective effects and have the potential to be used in the development of new functional foods. An overview of the synthesis of these small chiral molecules and their molecular properties is presented. The occurrence, taste, and bioactivity of all simple naturally occurring 2,5-DKPs to date have been reviewed and those found in food from yeasts, fungi, and bacteria that have been used in food preparation or contamination, as well as metabolites of sweeteners and antibiotics added to food are also reviewed.
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Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Piperazinas / Bebidas / Análisis de los Alimentos Límite: Animals / Humans Idioma: En Revista: Crit Rev Food Sci Nutr Asunto de la revista: CIENCIAS DA NUTRICAO Año: 2017 Tipo del documento: Article País de afiliación: Reino Unido Pais de publicación: Estados Unidos
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Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Piperazinas / Bebidas / Análisis de los Alimentos Límite: Animals / Humans Idioma: En Revista: Crit Rev Food Sci Nutr Asunto de la revista: CIENCIAS DA NUTRICAO Año: 2017 Tipo del documento: Article País de afiliación: Reino Unido Pais de publicación: Estados Unidos