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The epigenetic modifier EZH2 controls melanoma growth and metastasis through silencing of distinct tumour suppressors.
Zingg, Daniel; Debbache, Julien; Schaefer, Simon M; Tuncer, Eylul; Frommel, Sandra C; Cheng, Phil; Arenas-Ramirez, Natalia; Haeusel, Jessica; Zhang, Yudong; Bonalli, Mario; McCabe, Michael T; Creasy, Caretha L; Levesque, Mitchell P; Boyman, Onur; Santoro, Raffaella; Shakhova, Olga; Dummer, Reinhard; Sommer, Lukas.
Afiliación
  • Zingg D; Cell and Developmental Biology, Institute of Anatomy, University of Zurich, Winterthurerstrasse 190, 8057 Zürich, Switzerland.
  • Debbache J; Cell and Developmental Biology, Institute of Anatomy, University of Zurich, Winterthurerstrasse 190, 8057 Zürich, Switzerland.
  • Schaefer SM; Cell and Developmental Biology, Institute of Anatomy, University of Zurich, Winterthurerstrasse 190, 8057 Zürich, Switzerland.
  • Tuncer E; Cell and Developmental Biology, Institute of Anatomy, University of Zurich, Winterthurerstrasse 190, 8057 Zürich, Switzerland.
  • Frommel SC; Institute of Veterinary Biochemistry and Molecular Biology, University of Zurich, Winterthurerstrasse 190, 8057 Zürich, Switzerland.
  • Cheng P; Department of Dermatology, University Hospital Zurich, Gloriastrasse 31, 8091 Zürich, Switzerland.
  • Arenas-Ramirez N; Department of Immunology, University Hospital Zurich, Gloriastrasse 30, 8091 Zürich, Switzerland.
  • Haeusel J; Cell and Developmental Biology, Institute of Anatomy, University of Zurich, Winterthurerstrasse 190, 8057 Zürich, Switzerland.
  • Zhang Y; Cell and Developmental Biology, Institute of Anatomy, University of Zurich, Winterthurerstrasse 190, 8057 Zürich, Switzerland.
  • Bonalli M; Cell and Developmental Biology, Institute of Anatomy, University of Zurich, Winterthurerstrasse 190, 8057 Zürich, Switzerland.
  • McCabe MT; Cancer Epigenetics Discovery Performance Unit, Cancer Research, Oncology R&D, GlaxoSmithKline, 1250 South Collegeville Road, Collegeville, Pennsylvania 19426, USA.
  • Creasy CL; Cancer Epigenetics Discovery Performance Unit, Cancer Research, Oncology R&D, GlaxoSmithKline, 1250 South Collegeville Road, Collegeville, Pennsylvania 19426, USA.
  • Levesque MP; Department of Dermatology, University Hospital Zurich, Gloriastrasse 31, 8091 Zürich, Switzerland.
  • Boyman O; Department of Immunology, University Hospital Zurich, Gloriastrasse 30, 8091 Zürich, Switzerland.
  • Santoro R; Institute of Veterinary Biochemistry and Molecular Biology, University of Zurich, Winterthurerstrasse 190, 8057 Zürich, Switzerland.
  • Shakhova O; 1] Cell and Developmental Biology, Institute of Anatomy, University of Zurich, Winterthurerstrasse 190, 8057 Zürich, Switzerland [2] Department of Oncology, University Hospital Zurich, Rämistrasse 100, 8091 Zürich, Switzerland.
  • Dummer R; Department of Dermatology, University Hospital Zurich, Gloriastrasse 31, 8091 Zürich, Switzerland.
  • Sommer L; Cell and Developmental Biology, Institute of Anatomy, University of Zurich, Winterthurerstrasse 190, 8057 Zürich, Switzerland.
Nat Commun ; 6: 6051, 2015 Jan 22.
Article en En | MEDLINE | ID: mdl-25609585

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Neoplasias Cutáneas / Silenciador del Gen / Complejo Represivo Polycomb 2 / Melanoma Límite: Animals / Female / Humans Idioma: En Revista: Nat Commun Asunto de la revista: BIOLOGIA / CIENCIA Año: 2015 Tipo del documento: Article País de afiliación: Suiza Pais de publicación: Reino Unido

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Neoplasias Cutáneas / Silenciador del Gen / Complejo Represivo Polycomb 2 / Melanoma Límite: Animals / Female / Humans Idioma: En Revista: Nat Commun Asunto de la revista: BIOLOGIA / CIENCIA Año: 2015 Tipo del documento: Article País de afiliación: Suiza Pais de publicación: Reino Unido