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Synaptojanin 2 is a druggable mediator of metastasis and the gene is overexpressed and amplified in breast cancer.
Ben-Chetrit, Nir; Chetrit, David; Russell, Roslin; Körner, Cindy; Mancini, Maicol; Abdul-Hai, Ali; Itkin, Tomer; Carvalho, Silvia; Cohen-Dvashi, Hadas; Koestler, Wolfgang J; Shukla, Kirti; Lindzen, Moshit; Kedmi, Merav; Lauriola, Mattia; Shulman, Ziv; Barr, Haim; Seger, Dalia; Ferraro, Daniela A; Pareja, Fresia; Gil-Henn, Hava; Lapidot, Tsvee; Alon, Ronen; Milanezi, Fernanda; Symons, Marc; Ben-Hamo, Rotem; Efroni, Sol; Schmitt, Fernando; Wiemann, Stefan; Caldas, Carlos; Ehrlich, Marcelo; Yarden, Yosef.
Afiliación
  • Ben-Chetrit N; Department of Biological Regulation, Weizmann Institute of Science, Rehovot 76100, Israel.
  • Chetrit D; Department of Cell Research and Immunology, George Wise Faculty of Life Sciences, Tel Aviv University, Tel Aviv 69978, Israel.
  • Russell R; Department of Oncology and Cancer Research UK Cambridge Institute, University of Cambridge, Li Ka Shing Centre, Cambridge CB2 0RE, UK.
  • Körner C; Division of Molecular Genome Analysis, German Cancer Research Centre (DKFZ), Heidelberg 69120, Germany.
  • Mancini M; Department of Biological Regulation, Weizmann Institute of Science, Rehovot 76100, Israel.
  • Abdul-Hai A; Kaplan Medical Center, Rehovot 76100, Israel.
  • Itkin T; Department of Immunology, Weizmann Institute of Science, Rehovot 76100, Israel.
  • Carvalho S; Department of Biological Regulation, Weizmann Institute of Science, Rehovot 76100, Israel.
  • Cohen-Dvashi H; Department of Biological Regulation, Weizmann Institute of Science, Rehovot 76100, Israel.
  • Koestler WJ; Department of Biological Regulation, Weizmann Institute of Science, Rehovot 76100, Israel.
  • Shukla K; Division of Molecular Genome Analysis, German Cancer Research Centre (DKFZ), Heidelberg 69120, Germany.
  • Lindzen M; Department of Biological Regulation, Weizmann Institute of Science, Rehovot 76100, Israel.
  • Kedmi M; Department of Biological Regulation, Weizmann Institute of Science, Rehovot 76100, Israel.
  • Lauriola M; Department of Biological Regulation, Weizmann Institute of Science, Rehovot 76100, Israel.
  • Shulman Z; Department of Immunology, Weizmann Institute of Science, Rehovot 76100, Israel.
  • Barr H; INCPM, Weizmann Institute of Science, Rehovot 76100, Israel.
  • Seger D; Department of Biological Regulation, Weizmann Institute of Science, Rehovot 76100, Israel.
  • Ferraro DA; Department of Biological Regulation, Weizmann Institute of Science, Rehovot 76100, Israel.
  • Pareja F; Department of Biological Regulation, Weizmann Institute of Science, Rehovot 76100, Israel.
  • Gil-Henn H; Faculty of Medicine, Bar-Ilan University, Safed 13115, Israel.
  • Lapidot T; Department of Immunology, Weizmann Institute of Science, Rehovot 76100, Israel.
  • Alon R; Department of Immunology, Weizmann Institute of Science, Rehovot 76100, Israel.
  • Milanezi F; IPATIMUP, University of Porto, Porto 4200-465, Portugal.
  • Symons M; Center for Oncology and Cell Biology, The Feinstein Institute for Medical Research, Manhasset, NY 11030, USA.
  • Ben-Hamo R; The Mina and Everard Goodman Faculty of Life Science, Bar Ilan University, Ramat-Gan 52900, Israel.
  • Efroni S; The Mina and Everard Goodman Faculty of Life Science, Bar Ilan University, Ramat-Gan 52900, Israel.
  • Schmitt F; IPATIMUP, University of Porto, Porto 4200-465, Portugal.
  • Wiemann S; Division of Molecular Genome Analysis, German Cancer Research Centre (DKFZ), Heidelberg 69120, Germany.
  • Caldas C; Department of Oncology and Cancer Research UK Cambridge Institute, University of Cambridge, Li Ka Shing Centre, Cambridge CB2 0RE, UK.
  • Ehrlich M; Department of Cell Research and Immunology, George Wise Faculty of Life Sciences, Tel Aviv University, Tel Aviv 69978, Israel.
  • Yarden Y; Department of Biological Regulation, Weizmann Institute of Science, Rehovot 76100, Israel. yosef.yarden@weizmann.ac.il.
Sci Signal ; 8(360): ra7, 2015 Jan 20.
Article en En | MEDLINE | ID: mdl-25605973
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Neoplasias de la Mama / Regulación Neoplásica de la Expresión Génica / Monoéster Fosfórico Hidrolasas / Metástasis de la Neoplasia Tipo de estudio: Prognostic_studies Límite: Animals / Female / Humans Idioma: En Revista: Sci Signal Asunto de la revista: CIENCIA / FISIOLOGIA Año: 2015 Tipo del documento: Article País de afiliación: Israel Pais de publicación: Estados Unidos
Texto completo
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Neoplasias de la Mama / Regulación Neoplásica de la Expresión Génica / Monoéster Fosfórico Hidrolasas / Metástasis de la Neoplasia Tipo de estudio: Prognostic_studies Límite: Animals / Female / Humans Idioma: En Revista: Sci Signal Asunto de la revista: CIENCIA / FISIOLOGIA Año: 2015 Tipo del documento: Article País de afiliación: Israel Pais de publicación: Estados Unidos