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Primary MPNST in Childhood- A Rare Case Report.
Kudesia, Sandip; Bhardwaj, Aparna; Thakur, Brijesh; Kishore, Sanjeev; Bahal, Neelima.
Afiliación
  • Kudesia S; Professor & Head, Department of Pathology, SGRRIM & HS , Dehradun, Uttrakhand, India .
  • Bhardwaj A; Associate Professor, Department of Pathology, SGRRIM & HS , Dehradun, Uttrakhand, India .
  • Thakur B; Assistant Professor, Department of Pathology, SGRRIM & HS , Dehradun, Uttrakhand, India .
  • Kishore S; Professor, Department of Pathology, SGRRIM & HS , Dehradun, Uttrakhand, India .
  • Bahal N; Juniour resident II, Department of Pathology, SGRRIM & HS , Dehradun, Uttrakhand, India .
J Clin Diagn Res ; 8(11): FD01-2, 2014 Nov.
Article en En | MEDLINE | ID: mdl-25584230
Malignant peripheral nerve sheath tumour usually occurs between 20-50 years of age, comprising about 5-10% of soft tissue sarcomas. Only 1.7% of them have been reported to occur in children < 5 months of age according to the literature. Here, we are describing 18 mnth old male child presented with a swelling in the lower back. MRI showed a sacrcoccygeal swelling extending to and communicating with CSF at lower sacral level. Birth history of the child was normal with normal apgar score. The histological diagnosis was malignant peripheral nerve sheath tumour. IHC showed focal positivity of GFAP and S100. Primary spinal MPNST in children are rarer. A careful neurological examination is warranted in children. Early diagnosis and referral to multidisciplinary team are important in ensuring the best diagnosis and optimal therapy in this young age.
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Tipo de estudio: Screening_studies Idioma: En Revista: J Clin Diagn Res Año: 2014 Tipo del documento: Article País de afiliación: India Pais de publicación: India

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Tipo de estudio: Screening_studies Idioma: En Revista: J Clin Diagn Res Año: 2014 Tipo del documento: Article País de afiliación: India Pais de publicación: India