Your browser doesn't support javascript.
loading
The Association between Diabetic Retinopathy and Levels of Ischemia-Modified Albumin, Total Thiol, Total Antioxidant Capacity, and Total Oxidative Stress in Serum and Aqueous Humor.
Kirboga, Kadir; Ozec, Ayse V; Kosker, Mustafa; Dursun, Ayhan; Toker, Mustafa I; Aydin, Huseyin; Erdogan, Haydar; Topalkara, Aysen; Arici, Mustafa K.
Afiliación
  • Kirboga K; Department of Ophthalmology, Cumhuriyet University School of Medicine, 58140 Sivas, Turkey.
  • Ozec AV; Department of Ophthalmology, Cumhuriyet University School of Medicine, 58140 Sivas, Turkey.
  • Kosker M; Department of Ophthalmology, Ulus State Hospital, Ankara, Turkey.
  • Dursun A; Department of Ophthalmology, Cumhuriyet University School of Medicine, 58140 Sivas, Turkey.
  • Toker MI; Department of Ophthalmology, Cumhuriyet University School of Medicine, 58140 Sivas, Turkey.
  • Aydin H; Department of Biochemistry, Cumhuriyet University School of Medicine, 58140 Sivas, Turkey.
  • Erdogan H; Department of Ophthalmology, Cumhuriyet University School of Medicine, 58140 Sivas, Turkey.
  • Topalkara A; Department of Ophthalmology, Cumhuriyet University School of Medicine, 58140 Sivas, Turkey.
  • Arici MK; Department of Ophthalmology, Cumhuriyet University School of Medicine, 58140 Sivas, Turkey.
J Ophthalmol ; 2014: 820853, 2014.
Article en En | MEDLINE | ID: mdl-25580282
Purpose. To investigate the oxidant and antioxidant status of patients with type 2 diabetes mellitus and nonproliferative diabetic retinopathy (DRP). Methods. Forty-four patients who had cataract surgery were enrolled in the study. We included 22 patients with DRP in one group and 22 patients in the control group. Samples of aqueous humor and serum were taken from all patients. Serum and aqueous ischemia-modified albumin (IMA), total thiol, total antioxidant capacity (TAC), and total oxidative stress (TOS) levels were compared in two groups. Results. Median serum IMA levels were 44.80 absorbance units in the DRP group and 40.15 absorbance units in the control group (P = 0.031). Median serum total thiol levels in the DRP group were significantly less than those in the control group (3051.13 and 3910.12, resp., P = 0.004). Mean TOS levels in the serum were 2.93 ± 0.19 in the DRP group and 2.61 ± 0.26 in the control group (P = 0.039). The differences in mean total thiol, TAC, and TOS levels in the aqueous humor and mean TAC levels in the serum were not statistically significant. Conclusion. IMA, total thiol, and TOS levels in the serum might be useful markers in monitoring the risk of DRP development.
Texto completo
Añadir a Mi BVS
Imprimir
XML
PubMed Links
Buscar en Google

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Tipo de estudio: Risk_factors_studies Idioma: En Revista: J Ophthalmol Año: 2014 Tipo del documento: Article País de afiliación: Turquía Pais de publicación: Estados Unidos
Texto completo
Añadir a Mi BVS
Imprimir
XML
PubMed Links
Buscar en Google

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Tipo de estudio: Risk_factors_studies Idioma: En Revista: J Ophthalmol Año: 2014 Tipo del documento: Article País de afiliación: Turquía Pais de publicación: Estados Unidos