Your browser doesn't support javascript.
loading
CD24 expression predicts poor prognosis for patients with cutaneous malignant melanoma.
Tang, Ming-Rui; Wang, Yu-Xin; Guo, Shu; Han, Si-Yuan; Li, He-Huan; Jin, Shi-Feng.
Afiliación
  • Tang MR; Department of Plastic Surgery, The First Hospital of China Medical University 155 Nanjing North Street, Heping District, Shenyang City 110001, Liaoning Province, China.
  • Wang YX; Department of Plastic Surgery, The First Hospital of China Medical University 155 Nanjing North Street, Heping District, Shenyang City 110001, Liaoning Province, China.
  • Guo S; Department of Plastic Surgery, The First Hospital of China Medical University 155 Nanjing North Street, Heping District, Shenyang City 110001, Liaoning Province, China.
  • Han SY; Department of Plastic Surgery, The First Hospital of China Medical University 155 Nanjing North Street, Heping District, Shenyang City 110001, Liaoning Province, China.
  • Li HH; Department of Plastic Surgery, The First Hospital of China Medical University 155 Nanjing North Street, Heping District, Shenyang City 110001, Liaoning Province, China.
  • Jin SF; Department of Plastic Surgery, The First Hospital of China Medical University 155 Nanjing North Street, Heping District, Shenyang City 110001, Liaoning Province, China.
Int J Clin Exp Med ; 7(11): 4337-41, 2014.
Article en En | MEDLINE | ID: mdl-25550951
Cutaneous malignant melanoma represents the major cause of mortality among skin cancers. Metastasis-associated protein CD24 is a small, heavily glycosylated cell surface protein that is overexpressed in various human malignancies. The present study was designed to determine the roles of CD24 in cutaneous malignant melanoma. The levels of CD24 mRNA and protein in cutaneous malignant melanoma tissues were detected by RT-PCR, Western blot and IHC. In patient samples, the levels of CD24 mRNA and protein were higher in cancer tissues than that in normal tissues. CD24 expression decreased the survival time of the patients with melanoma. Taken together, these results suggest that CD24 may be used as a new drug target for cutaneous malignant melanoma.
Palabras clave
Texto completo
Añadir a Mi BVS
Imprimir
XML
PubMed Links
Buscar en Google

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Tipo de estudio: Prognostic_studies / Risk_factors_studies Idioma: En Revista: Int J Clin Exp Med Año: 2014 Tipo del documento: Article País de afiliación: China Pais de publicación: Estados Unidos
Texto completo
Añadir a Mi BVS
Imprimir
XML
PubMed Links
Buscar en Google

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Tipo de estudio: Prognostic_studies / Risk_factors_studies Idioma: En Revista: Int J Clin Exp Med Año: 2014 Tipo del documento: Article País de afiliación: China Pais de publicación: Estados Unidos