The hypoxia-inducible miR-429 regulates hypoxia-inducible factor-1&#945; expression in human endothelial cells through a negative feedback loop.

Bartoszewska, Sylwia; Kochan, Kinga; Piotrowski, Arkadiusz; Kamysz, Wojciech; Ochocka, Renata J; Collawn, James F; Bartoszewski, Rafal

The hypoxia-inducible miR-429 regulates hypoxia-inducible factor-1α expression in human endothelial cells through a negative feedback loop.

Bartoszewska, Sylwia; Kochan, Kinga; Piotrowski, Arkadiusz; Kamysz, Wojciech; Ochocka, Renata J; Collawn, James F; Bartoszewski, Rafal.

Afiliación

Bartoszewska S; Departments of *Inorganic Chemistry and Biology and Pharmaceutical Botany, Medical University of Gdansk, Gdansk, Poland; and Department of Cell, Developmental and Integrative Biology, University of Alabama, Birmingham, Birmingham, Alabama, USA.
Kochan K; Departments of *Inorganic Chemistry and Biology and Pharmaceutical Botany, Medical University of Gdansk, Gdansk, Poland; and Department of Cell, Developmental and Integrative Biology, University of Alabama, Birmingham, Birmingham, Alabama, USA.
Piotrowski A; Departments of *Inorganic Chemistry and Biology and Pharmaceutical Botany, Medical University of Gdansk, Gdansk, Poland; and Department of Cell, Developmental and Integrative Biology, University of Alabama, Birmingham, Birmingham, Alabama, USA.
Kamysz W; Departments of *Inorganic Chemistry and Biology and Pharmaceutical Botany, Medical University of Gdansk, Gdansk, Poland; and Department of Cell, Developmental and Integrative Biology, University of Alabama, Birmingham, Birmingham, Alabama, USA.
Ochocka RJ; Departments of *Inorganic Chemistry and Biology and Pharmaceutical Botany, Medical University of Gdansk, Gdansk, Poland; and Department of Cell, Developmental and Integrative Biology, University of Alabama, Birmingham, Birmingham, Alabama, USA.
Collawn JF; Departments of *Inorganic Chemistry and Biology and Pharmaceutical Botany, Medical University of Gdansk, Gdansk, Poland; and Department of Cell, Developmental and Integrative Biology, University of Alabama, Birmingham, Birmingham, Alabama, USA jcollawn@uab.edu rafalbar@gumed.edu.pl.
Bartoszewski R; Departments of *Inorganic Chemistry and Biology and Pharmaceutical Botany, Medical University of Gdansk, Gdansk, Poland; and Department of Cell, Developmental and Integrative Biology, University of Alabama, Birmingham, Birmingham, Alabama, USA jcollawn@uab.edu rafalbar@gumed.edu.pl.

FASEB J ; 29(4): 1467-79, 2015 Apr.

Article en En | MEDLINE | ID: mdl-25550463

Asunto(s)

Hipoxia de la Célula/genética; Hipoxia de la Célula/fisiología; Subunidad alfa del Factor 1 Inducible por Hipoxia/genética; MicroARNs/genética; MicroARNs/metabolismo; Factores de Transcripción con Motivo Hélice-Asa-Hélice Básico/genética; Factores de Transcripción con Motivo Hélice-Asa-Hélice Básico/metabolismo; Retroalimentación Fisiológica; Células Endoteliales de la Vena Umbilical Humana; Humanos; Subunidad alfa del Factor 1 Inducible por Hipoxia/antagonistas & inhibidores; Subunidad alfa del Factor 1 Inducible por Hipoxia/metabolismo; Prolina Dioxigenasas del Factor Inducible por Hipoxia/genética; Oxigenasas de Función Mixta/genética; Modelos Biológicos; Neovascularización Fisiológica; Proteolisis; Estabilidad del ARN; ARN Mensajero/genética; ARN Mensajero/metabolismo; Proteínas Represoras/genética; Factor A de Crecimiento Endotelial Vascular/genética

Palabras clave

HIF-2; VEGF A; angiogenesis; hypoxamiR; miRNA

Texto completo

Añadir a Mi BVS

Imprimir

XML

PubMed Links

Buscar en Google

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Hipoxia de la Célula / MicroARNs / Subunidad alfa del Factor 1 Inducible por Hipoxia Tipo de estudio: Prognostic_studies Límite: Humans Idioma: En Revista: FASEB J Asunto de la revista: BIOLOGIA / FISIOLOGIA Año: 2015 Tipo del documento: Article País de afiliación: Estados Unidos Pais de publicación: Estados Unidos

Texto completo

Añadir a Mi BVS

Imprimir

XML

PubMed Links

Buscar en Google