Synthesis, characterization, and anticancer activity of new quinazoline derivatives against MCF-7 cells.

Faraj, Fadhil Lafta; Zahedifard, Maryam; Paydar, Mohammadjavad; Looi, Chung Yeng; Abdul Majid, Nazia; Ali, Hapipah Mohd; Ahmad, Noraini; Gwaram, Nura Suleiman; Abdulla, Mahmood Ameen

Faraj, Fadhil Lafta; Zahedifard, Maryam; Paydar, Mohammadjavad; Looi, Chung Yeng; Abdul Majid, Nazia; Ali, Hapipah Mohd; Ahmad, Noraini; Gwaram, Nura Suleiman; Abdulla, Mahmood Ameen.

Afiliación

Faraj FL; Department of Chemistry, Faculty of Science, University of Malaya, 50603 Kuala Lumpur, Malaysia ; Department of Chemistry, Faculty of Science, University of Diyala, Diyala Governorate, Iraq.
Zahedifard M; Institute of Biological Sciences, Faculty of Science, University of Malaya, 50603 Kuala Lumpur, Malaysia.
Paydar M; Department of Pharmacology, Faculty of Medicine, University of Malaya, 50603 Kuala Lumpur, Malaysia.
Looi CY; Department of Pharmacology, Faculty of Medicine, University of Malaya, 50603 Kuala Lumpur, Malaysia.
Abdul Majid N; Institute of Biological Sciences, Faculty of Science, University of Malaya, 50603 Kuala Lumpur, Malaysia.
Ali HM; Department of Chemistry, Faculty of Science, University of Malaya, 50603 Kuala Lumpur, Malaysia.
Ahmad N; Department of Chemistry, Faculty of Science, University of Malaya, 50603 Kuala Lumpur, Malaysia.
Gwaram NS; Department of Chemistry, Faculty of Science, University of Malaya, 50603 Kuala Lumpur, Malaysia.
Abdulla MA; Department of Biomedical Science, Faculty of Medicine, University of Malaya, 50603 Kuala Lumpur, Malaysia.

ScientificWorldJournal ; 2014: 212096, 2014.

Article en En | MEDLINE | ID: mdl-25548779

Asunto(s)

Antineoplásicos/síntesis química; Antineoplásicos/farmacología; Quinazolinas/síntesis química; Quinazolinas/farmacología; Absorción Fisicoquímica; Animales; Antineoplásicos/química; Antineoplásicos/toxicidad; Espectroscopía de Resonancia Magnética con Carbono-13; Caspasas/metabolismo; Ciclo Celular/efectos de los fármacos; Cristalografía por Rayos X; Activación Enzimática/efectos de los fármacos; Femenino; Humanos; Concentración 50 Inhibidora; Luminiscencia; Células MCF-7; Ratones; Microscopía Fluorescente; Mitocondrias/metabolismo; FN-kappa B/metabolismo; Transporte de Proteínas; Espectroscopía de Protones por Resonancia Magnética; Quinazolinas/química; Quinazolinas/toxicidad; Especies Reactivas de Oxígeno/metabolismo; Espectrofotometría Infrarroja; Factores de Tiempo; Pruebas de Toxicidad Aguda

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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Quinazolinas / Antineoplásicos Límite: Animals / Female / Humans Idioma: En Revista: ScientificWorldJournal Asunto de la revista: MEDICINA Año: 2014 Tipo del documento: Article País de afiliación: Irak Pais de publicación: Estados Unidos

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