Development of a protective dermal drug delivery system for therapeutic DNAzymes.

Marquardt, Kay; Eicher, Anna-Carola; Dobler, Dorota; Mäder, Ulf; Schmidts, Thomas; Renz, Harald; Runkel, Frank

Marquardt, Kay; Eicher, Anna-Carola; Dobler, Dorota; Mäder, Ulf; Schmidts, Thomas; Renz, Harald; Runkel, Frank.

Afiliación

Marquardt K; Institute of Bioprocess Engineering and Pharmaceutical Technology, University of Applied Sciences Mittelhessen, Wiesenstrasse 14, 35390 Giessen, Germany. Electronic address: Kay.Marquardt@kmub.thm.de.
Eicher AC; Institute of Bioprocess Engineering and Pharmaceutical Technology, University of Applied Sciences Mittelhessen, Wiesenstrasse 14, 35390 Giessen, Germany.
Dobler D; Institute of Bioprocess Engineering and Pharmaceutical Technology, University of Applied Sciences Mittelhessen, Wiesenstrasse 14, 35390 Giessen, Germany.
Mäder U; Institute of Medical Physics and Radiation Protection, University of Applied Sciences Mittelhessen, Wiesenstrasse 14, 35390 Giessen, Germany.
Schmidts T; Institute of Bioprocess Engineering and Pharmaceutical Technology, University of Applied Sciences Mittelhessen, Wiesenstrasse 14, 35390 Giessen, Germany.
Renz H; Institute of Laboratory Medicine and Pathobiochemistry, Molecular Diagnostic, Baldinger Strasse, 35043 Marburg, Philipps-University Marburg, Germany.
Runkel F; Institute of Bioprocess Engineering and Pharmaceutical Technology, University of Applied Sciences Mittelhessen, Wiesenstrasse 14, 35390 Giessen, Germany.

Int J Pharm ; 479(1): 150-8, 2015 Feb 01.

Article en En | MEDLINE | ID: mdl-25541146

Asunto(s)

ADN Catalítico/administración & dosificación; Sistemas de Liberación de Medicamentos; Administración Cutánea; Animales; Línea Celular; Quitosano/química; Citoplasma/metabolismo; ADN Catalítico/química; ADN Catalítico/farmacología; Estabilidad de Enzimas; Humanos; Técnicas In Vitro; Queratinocitos/efectos de los fármacos; Queratinocitos/metabolismo; Queratosis Actínica; Liposomas; Piel/metabolismo; Absorción Cutánea; Sus scrofa

Palabras clave

Benzoic acid (PubChem CID: 243); Benzyl alcohol (PubChem CID: 244); Chitosan; Chitosan (PubChem CID: 21896651); DNAzyme; DNase; Drug delivery system; Methylparaben (PubChem CID: 7456); Oleyl oleate (PubChem CID: 543844); Phenoxy ethanol (PubChem CID: 31236); Phosphatidylcholin (PubChem CID: 45266626); Polyplex; Propylene glycol (PubChem CID: 1030); Propylparaben (PubChem CID: 7175); Submicron emulsion

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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Sistemas de Liberación de Medicamentos / ADN Catalítico Límite: Animals / Humans Idioma: En Revista: Int J Pharm Año: 2015 Tipo del documento: Article Pais de publicación: Países Bajos

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