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Cetacean morbillivirus: current knowledge and future directions.
Van Bressem, Marie-Françoise; Duignan, Pádraig J; Banyard, Ashley; Barbieri, Michelle; Colegrove, Kathleen M; De Guise, Sylvain; Di Guardo, Giovanni; Dobson, Andrew; Domingo, Mariano; Fauquier, Deborah; Fernandez, Antonio; Goldstein, Tracey; Grenfell, Bryan; Groch, Kátia R; Gulland, Frances; Jensen, Brenda A; Jepson, Paul D; Hall, Ailsa; Kuiken, Thijs; Mazzariol, Sandro; Morris, Sinead E; Nielsen, Ole; Raga, Juan A; Rowles, Teresa K; Saliki, Jeremy; Sierra, Eva; Stephens, Nahiid; Stone, Brett; Tomo, Ikuko; Wang, Jianning; Waltzek, Thomas; Wellehan, James F X.
Afiliación
  • Van Bressem MF; Cetacean Conservation Medicine Group (CMED), Peruvian Centre for Cetacean Research (CEPEC), Pucusana, Lima 20, Peru. mfb.cmed@gmail.com.
  • Duignan PJ; Department of Ecosystem and Public Health, University of Calgary, Calgary, AL T2N 4Z6, Canada. ppjduign@ucalgary.ca.
  • Banyard A; Wildlife Zoonoses and Vector Borne Disease Research Group, Animal and Plant Health Agency (APHA), Weybridge, Surrey KT15 3NB, UK. ashley.banyard@apha.gsi.gov.uk.
  • Barbieri M; The Marine Mammal Centre, Sausalito, CA 94965, USA. michelle.barbieri@noaa.gov.
  • Colegrove KM; Zoological Pathology Program, College of Veterinary Medicine, University of Illinois at Maywood, IL 60153 , USA. katie.colegrove@gmail.com.
  • De Guise S; Department of Pathobiology and Veterinary Science, and Connecticut Sea Grant College Program, University of Connecticut, Storrs, CT 06269, USA. sylvain.deguise@uconn.edu.
  • Di Guardo G; Faculty of Veterinary Medicine, University of Teramo, 64100 Teramo, Italy. gdiguardo@unite.it.
  • Dobson A; Department of Ecology and Evolutionary Biology, Princeton University, Princeton, NJ 08544, USA. dobson@princeton.edu.
  • Domingo M; Centre de Recerca en Sanitat Animal (CReSA), Autonomous University of Barcelona, Bellaterra, Barcelona 08193, Spain. Mariano.Domingo@cresa.uab.cat.
  • Fauquier D; Cetacean Conservation Medicine Group (CMED), Peruvian Centre for Cetacean Research (CEPEC), Pucusana, Lima 20, Peru.
  • Fernandez A; Cetacean Conservation Medicine Group (CMED), Peruvian Centre for Cetacean Research (CEPEC), Pucusana, Lima 20, Peru.
  • Goldstein T; Cetacean Conservation Medicine Group (CMED), Peruvian Centre for Cetacean Research (CEPEC), Pucusana, Lima 20, Peru. ppjduign@ucalgary.ca.
  • Grenfell B; Department of Ecology and Evolutionary Biology, Princeton University, Princeton, NJ 08544, USA. grenfell@princeton.edu.
  • Groch KR; Cetacean Conservation Medicine Group (CMED), Peruvian Centre for Cetacean Research (CEPEC), Pucusana, Lima 20, Peru. katie.colegrove@gmail.com.
  • Gulland F; The Marine Mammal Centre, Sausalito, CA 94965, USA. sylvain.deguise@uconn.edu.
  • Jensen BA; Cetacean Conservation Medicine Group (CMED), Peruvian Centre for Cetacean Research (CEPEC), Pucusana, Lima 20, Peru. gdiguardo@unite.it.
  • Jepson PD; Cetacean Conservation Medicine Group (CMED), Peruvian Centre for Cetacean Research (CEPEC), Pucusana, Lima 20, Peru. paul.jepson@ioz.ac.uk.
  • Hall A; Cetacean Conservation Medicine Group (CMED), Peruvian Centre for Cetacean Research (CEPEC), Pucusana, Lima 20, Peru. Mariano.Domingo@cresa.uab.cat.
  • Kuiken T; Department of Ecosystem and Public Health, University of Calgary, Calgary, AL T2N 4Z6, Canada. ppjduign@ucalgary.ca.
  • Mazzariol S; Department of Ecosystem and Public Health, University of Calgary, Calgary, AL T2N 4Z6, Canada. ppjduign@ucalgary.ca.
  • Morris SE; Department of Ecology and Evolutionary Biology, Princeton University, Princeton, NJ 08544, USA. semorris@princeton.edu.
  • Nielsen O; Department of Ecosystem and Public Health, University of Calgary, Calgary, AL T2N 4Z6, Canada. ppjduign@ucalgary.ca.
  • Raga JA; Department of Ecosystem and Public Health, University of Calgary, Calgary, AL T2N 4Z6, Canada. ashley.banyard@apha.gsi.gov.uk.
  • Rowles TK; Cetacean Conservation Medicine Group (CMED), Peruvian Centre for Cetacean Research (CEPEC), Pucusana, Lima 20, Peru.
  • Saliki J; Department of Ecosystem and Public Health, University of Calgary, Calgary, AL T2N 4Z6, Canada. ppjduign@ucalgary.ca.
  • Sierra E; Cetacean Conservation Medicine Group (CMED), Peruvian Centre for Cetacean Research (CEPEC), Pucusana, Lima 20, Peru.
  • Stephens N; Department of Ecosystem and Public Health, University of Calgary, Calgary, AL T2N 4Z6, Canada. katie.colegrove@gmail.com.
  • Stone B; Department of Ecosystem and Public Health, University of Calgary, Calgary, AL T2N 4Z6, Canada. sylvain.deguise@uconn.edu.
  • Tomo I; Department of Ecosystem and Public Health, University of Calgary, Calgary, AL T2N 4Z6, Canada. gdiguardo@unite.it.
  • Wang J; Department of Ecosystem and Public Health, University of Calgary, Calgary, AL T2N 4Z6, Canada. ppjduign@ucalgary.ca.
  • Waltzek T; Department of Ecosystem and Public Health, University of Calgary, Calgary, AL T2N 4Z6, Canada. Mariano.Domingo@cresa.uab.cat.
  • Wellehan JF; Wildlife Zoonoses and Vector Borne Disease Research Group, Animal and Plant Health Agency (APHA), Weybridge, Surrey KT15 3NB, UK. ashley.banyard@apha.gsi.gov.uk.
Viruses ; 6(12): 5145-81, 2014 Dec 22.
Article en En | MEDLINE | ID: mdl-25533660
We review the molecular and epidemiological characteristics of cetacean morbillivirus (CeMV) and the diagnosis and pathogenesis of associated disease, with six different strains detected in cetaceans worldwide. CeMV has caused epidemics with high mortality in odontocetes in Europe, the USA and Australia. It represents a distinct species within the Morbillivirus genus. Although most CeMV strains are phylogenetically closely related, recent data indicate that morbilliviruses recovered from Indo-Pacific bottlenose dolphins (Tursiops aduncus), from Western Australia, and a Guiana dolphin (Sotalia guianensis), from Brazil, are divergent. The signaling lymphocyte activation molecule (SLAM) cell receptor for CeMV has been characterized in cetaceans. It shares higher amino acid identity with the ruminant SLAM than with the receptors of carnivores or humans, reflecting the evolutionary history of these mammalian taxa. In Delphinidae, three amino acid substitutions may result in a higher affinity for the virus. Infection is diagnosed by histology, immunohistochemistry, virus isolation, RT-PCR, and serology. Classical CeMV-associated lesions include bronchointerstitial pneumonia, encephalitis, syncytia, and lymphoid depletion associated with immunosuppression. Cetaceans that survive the acute disease may develop fatal secondary infections and chronic encephalitis. Endemically infected, gregarious odontocetes probably serve as reservoirs and vectors. Transmission likely occurs through the inhalation of aerosolized virus but mother to fetus transmission was also reported.
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Cetáceos / Infecciones por Morbillivirus / Morbillivirus Límite: Animals Idioma: En Revista: Viruses Año: 2014 Tipo del documento: Article País de afiliación: Perú Pais de publicación: Suiza
Texto completo
Añadir a Mi BVS
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PubMed Links
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Cetáceos / Infecciones por Morbillivirus / Morbillivirus Límite: Animals Idioma: En Revista: Viruses Año: 2014 Tipo del documento: Article País de afiliación: Perú Pais de publicación: Suiza