Surface modification of titanium with hydroxyapatite-heparin-BMP-2 enhances the efficacy of bone formation and osseointegration in vitro and in vivo.

Yang, Dae Hyeok; Lee, Deok-Won; Kwon, Yong-Dae; Kim, Hyun Joo; Chun, Heung Jae; Jang, Ju Woong; Khang, Gilson

Yang, Dae Hyeok; Lee, Deok-Won; Kwon, Yong-Dae; Kim, Hyun Joo; Chun, Heung Jae; Jang, Ju Woong; Khang, Gilson.

Afiliación

Yang DH; Institute of Cell and Tissue Engineering, College of Medicine, The Catholic University of Korea, Seoul, Republic of Korea.
Lee DW; Department of Oral and Maxillofacial Surgery, Kyung Hee University Dental Hospital at Gangdong, Kyung Hee University, Seoul, Republic of Korea.
Kwon YD; Department of Oral and Maxillofacial Surgery, Kyung Hee University Dental Hospital at Gangdong, Kyung Hee University, Seoul, Republic of Korea.
Kim HJ; Institute of Cell and Tissue Engineering, College of Medicine, The Catholic University of Korea, Seoul, Republic of Korea.
Chun HJ; Department of Biomedical Sciences, College of Medicine, The Catholic University of Korea, Seoul, Republic of Korea.
Jang JW; Institute of Cell and Tissue Engineering, College of Medicine, The Catholic University of Korea, Seoul, Republic of Korea.
Khang G; Department of Biomedical Sciences, College of Medicine, The Catholic University of Korea, Seoul, Republic of Korea.

J Tissue Eng Regen Med ; 9(9): 1067-77, 2015 Sep.

Article en En | MEDLINE | ID: mdl-25524250

Asunto(s)

Desarrollo Óseo; Proteína Morfogenética Ósea 2/química; Durapatita/química; Heparina/química; Oseointegración; Titanio/química; Fosfatasa Alcalina/metabolismo; Animales; Proteína Morfogenética Ósea 2/metabolismo; Línea Celular Tumoral; Humanos; Técnicas In Vitro; Microscopía Electrónica de Rastreo; Osteocalcina/genética; Espectroscopía de Fotoelectrones; ARN Mensajero/genética; Conejos; Propiedades de Superficie

Palabras clave

bone formation; bone morphogenetic protein-2; hydroxyapatite; in vitro; in vivo; osseointegration; surface-modified titanium

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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Titanio / Desarrollo Óseo / Heparina / Oseointegración / Durapatita / Proteína Morfogenética Ósea 2 Límite: Animals / Humans Idioma: En Revista: J Tissue Eng Regen Med Asunto de la revista: BIOTECNOLOGIA / HISTOLOGIA Año: 2015 Tipo del documento: Article Pais de publicación: Reino Unido

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