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Lysocin E is a new antibiotic that targets menaquinone in the bacterial membrane.
Hamamoto, Hiroshi; Urai, Makoto; Ishii, Kenichi; Yasukawa, Jyunichiro; Paudel, Atmika; Murai, Motoki; Kaji, Takuya; Kuranaga, Takefumi; Hamase, Kenji; Katsu, Takashi; Su, Jie; Adachi, Tatsuo; Uchida, Ryuji; Tomoda, Hiroshi; Yamada, Maki; Souma, Manabu; Kurihara, Hiroki; Inoue, Masayuki; Sekimizu, Kazuhisa.
Afiliación
  • Hamamoto H; Laboratory of Microbiology, Graduate School of Pharmaceutical Sciences, University of Tokyo, Tokyo, Japan.
  • Urai M; Laboratory of Microbiology, Graduate School of Pharmaceutical Sciences, University of Tokyo, Tokyo, Japan.
  • Ishii K; Laboratory of Microbiology, Graduate School of Pharmaceutical Sciences, University of Tokyo, Tokyo, Japan.
  • Yasukawa J; Laboratory of Microbiology, Graduate School of Pharmaceutical Sciences, University of Tokyo, Tokyo, Japan.
  • Paudel A; Laboratory of Microbiology, Graduate School of Pharmaceutical Sciences, University of Tokyo, Tokyo, Japan.
  • Murai M; Laboratory of Synthetic Medicinal Chemistry, Graduate School of Pharmaceutical Sciences, University of Tokyo, Tokyo, Japan.
  • Kaji T; Laboratory of Synthetic Medicinal Chemistry, Graduate School of Pharmaceutical Sciences, University of Tokyo, Tokyo, Japan.
  • Kuranaga T; Laboratory of Synthetic Medicinal Chemistry, Graduate School of Pharmaceutical Sciences, University of Tokyo, Tokyo, Japan.
  • Hamase K; Department of Drug Discovery and Evolution, Graduate School of Pharmaceutical Sciences, Kyushu University, Fukuoka, Japan.
  • Katsu T; Department of Pharmacy, Graduate School of Pharmacy, Yasuda Women's University, Hiroshima, Japan.
  • Su J; Laboratory of Microbiology, Graduate School of Pharmaceutical Sciences, University of Tokyo, Tokyo, Japan.
  • Adachi T; Laboratory of Microbiology, Graduate School of Pharmaceutical Sciences, University of Tokyo, Tokyo, Japan.
  • Uchida R; Department of Microbial Chemistry, Graduate School of Pharmaceutical Sciences, Kitasato University, Tokyo, Japan.
  • Tomoda H; Department of Microbial Chemistry, Graduate School of Pharmaceutical Sciences, Kitasato University, Tokyo, Japan.
  • Yamada M; 1] Department of Physiological Chemistry and Metabolism, Graduate School of Medicine, University of Tokyo, Tokyo, Japan. [2] Core Research for Evolutional Science and Technology, Japan Science and Technology Agency, Tokyo, Japan.
  • Souma M; MASIS Inc., Aomori, Japan.
  • Kurihara H; 1] Department of Physiological Chemistry and Metabolism, Graduate School of Medicine, University of Tokyo, Tokyo, Japan. [2] Core Research for Evolutional Science and Technology, Japan Science and Technology Agency, Tokyo, Japan.
  • Inoue M; Laboratory of Synthetic Medicinal Chemistry, Graduate School of Pharmaceutical Sciences, University of Tokyo, Tokyo, Japan.
  • Sekimizu K; Laboratory of Microbiology, Graduate School of Pharmaceutical Sciences, University of Tokyo, Tokyo, Japan.
Nat Chem Biol ; 11(2): 127-33, 2015 Feb.
Article en En | MEDLINE | ID: mdl-25485686
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Péptidos Cíclicos / Membrana Celular / Vitamina K 2 / Descubrimiento de Drogas / Bacterias Grampositivas / Antibacterianos Límite: Animals Idioma: En Revista: Nat Chem Biol Asunto de la revista: BIOLOGIA / QUIMICA Año: 2015 Tipo del documento: Article País de afiliación: Japón Pais de publicación: Estados Unidos
Texto completo
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XML
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Péptidos Cíclicos / Membrana Celular / Vitamina K 2 / Descubrimiento de Drogas / Bacterias Grampositivas / Antibacterianos Límite: Animals Idioma: En Revista: Nat Chem Biol Asunto de la revista: BIOLOGIA / QUIMICA Año: 2015 Tipo del documento: Article País de afiliación: Japón Pais de publicación: Estados Unidos