Typical and atypical neurodevelopment for face specialization: an FMRI study.
J Autism Dev Disord
; 45(6): 1725-41, 2015 Jun.
Article
en En
| MEDLINE
| ID: mdl-25479816
Individuals with autism spectrum disorder (ASD) and their relatives process faces differently from typically developed (TD) individuals. In an fMRI face-viewing task, TD and undiagnosed sibling (SIB) children (5-18 years) showed face specialization in the right amygdala and ventromedial prefrontal cortex, with left fusiform and right amygdala face specialization increasing with age in TD subjects. SIBs showed extensive antero-medial temporal lobe activation for faces that was not present in any other group, suggesting a potential compensatory mechanism. In ASD, face specialization was minimal but increased with age in the right fusiform and decreased with age in the left amygdala, suggesting atypical development of a frontal-amygdala-fusiform system which is strongly linked to detecting salience and processing facial information.
Texto completo:
1
Colección:
01-internacional
Base de datos:
MEDLINE
Asunto principal:
Lóbulo Temporal
/
Cara
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Reconocimiento Facial
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Trastorno del Espectro Autista
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Amígdala del Cerebelo
Tipo de estudio:
Observational_studies
Límite:
Adolescent
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Child
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Female
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Humans
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Male
Idioma:
En
Revista:
J Autism Dev Disord
Año:
2015
Tipo del documento:
Article
Pais de publicación:
Estados Unidos