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Patient quality of life and pain improve after autologous islet transplantation (AIT) for treatment of chronic pancreatitis: 53 patient series at the University of Arizona.
Georgiev, G; Beltran del Rio, M; Gruessner, A; Tiwari, M; Cercone, R; Delbridge, M; Grigsby, B; Gruessner, R; Rilo, H.
Afiliación
  • Georgiev G; Institute for Cellular Transplantation, Department of Surgery, University of Arizona, Tucson, AZ 85724, USA; Center for Diseases of the Pancreas, Northshore-LIJ, Department of Surgery, Manhasset, NY 11030, USA; Department of Physiological Sciences, University of Arizona, Tucson, AZ 85724, USA.
  • Beltran del Rio M; Institute for Cellular Transplantation, Department of Surgery, University of Arizona, Tucson, AZ 85724, USA; Center for Diseases of the Pancreas, Northshore-LIJ, Department of Surgery, Manhasset, NY 11030, USA.
  • Gruessner A; Institute for Cellular Transplantation, Department of Surgery, University of Arizona, Tucson, AZ 85724, USA; Mel & Enid Zuckerman College of Public Health, University of Arizona, Tucson 85724, AZ, USA.
  • Tiwari M; Institute for Cellular Transplantation, Department of Surgery, University of Arizona, Tucson, AZ 85724, USA; Center for Diseases of the Pancreas, Northshore-LIJ, Department of Surgery, Manhasset, NY 11030, USA.
  • Cercone R; Institute for Cellular Transplantation, Department of Surgery, University of Arizona, Tucson, AZ 85724, USA; Center for Diseases of the Pancreas, Northshore-LIJ, Department of Surgery, Manhasset, NY 11030, USA.
  • Delbridge M; Institute for Cellular Transplantation, Department of Surgery, University of Arizona, Tucson, AZ 85724, USA.
  • Grigsby B; Institute for Cellular Transplantation, Department of Surgery, University of Arizona, Tucson, AZ 85724, USA.
  • Gruessner R; Institute for Cellular Transplantation, Department of Surgery, University of Arizona, Tucson, AZ 85724, USA; Department of Surgery, University of Arizona, Tucson 85724, AZ, USA.
  • Rilo H; Institute for Cellular Transplantation, Department of Surgery, University of Arizona, Tucson, AZ 85724, USA; Center for Diseases of the Pancreas, Northshore-LIJ, Department of Surgery, Manhasset, NY 11030, USA; Department of Physiological Sciences, University of Arizona, Tucson, AZ 85724, USA; Depar
Pancreatology ; 15(1): 40-5, 2015.
Article en En | MEDLINE | ID: mdl-25455347
BACKGROUND/OBJECTIVES: Pancreatectomy with autologous islet transplantation has slowly been proving to be an effective way of treating chronic pancreatitis while lessening the effects of the concomitant surgical diabetes of pancreatectomy alone. Assessing patient quality of life and pain after the procedure is particularly important as intractable pain is the main complaint for which patients undergo total pancreatectomy. METHODS: We used the Rand SF-36 and McGill pain questionnaires, and Visual Analogue Scale to assess patients preoperatively for quality of life and pain resulting from life with chronic pancreatitis. After undergoing total pancreatectomy with autologous islet transplantation (TPAIT), patients were followed with surveys administered at 1 month, 6 months, and 1 year to evaluate changes in their quality of life and pain experienced. RESULTS: Significant improvement was reported in all components of every questionnaire within a year after surgery. Furthermore, patient reported mean scores on quality of life were found to fall within the range of the general population. CONCLUSIONS: From our experience with 53 patients at the University of Arizona, after pancreatectomy with autologous islet transplantation patients reported a higher quality of life when compared to preoperative values, as well as reduced levels of pain.
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Dolor Intratable / Dolor Postoperatorio / Pancreatectomía / Calidad de Vida / Dolor Abdominal / Trasplante de Islotes Pancreáticos / Pancreatitis Crónica Tipo de estudio: Diagnostic_studies / Evaluation_studies / Observational_studies / Prognostic_studies / Risk_factors_studies Aspecto: Patient_preference Límite: Adult / Female / Humans / Male / Middle aged Idioma: En Revista: Pancreatology Asunto de la revista: ENDOCRINOLOGIA / GASTROENTEROLOGIA Año: 2015 Tipo del documento: Article País de afiliación: Estados Unidos Pais de publicación: Suiza
Texto completo
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Dolor Intratable / Dolor Postoperatorio / Pancreatectomía / Calidad de Vida / Dolor Abdominal / Trasplante de Islotes Pancreáticos / Pancreatitis Crónica Tipo de estudio: Diagnostic_studies / Evaluation_studies / Observational_studies / Prognostic_studies / Risk_factors_studies Aspecto: Patient_preference Límite: Adult / Female / Humans / Male / Middle aged Idioma: En Revista: Pancreatology Asunto de la revista: ENDOCRINOLOGIA / GASTROENTEROLOGIA Año: 2015 Tipo del documento: Article País de afiliación: Estados Unidos Pais de publicación: Suiza