Rupatadine effectively prevents the histamine-induced up regulation of histamine H1R and bradykinin B2R receptor gene expression in the rat paw.

Molyva, Dimitra; Kalokasidis, Konstantinos; Poulios, Christos; Dedi, Hara; Karkavelas, George; Mirtsou, Vassiliki; Goulas, Antonis

Molyva, Dimitra; Kalokasidis, Konstantinos; Poulios, Christos; Dedi, Hara; Karkavelas, George; Mirtsou, Vassiliki; Goulas, Antonis.

Afiliación

Molyva D; 1st Department of Pharmacology, Faculty of Medicine, Aristotle University of Thessaloniki, Thessaloniki, Greece. Electronic address: dmolyva@yahoo.com.
Kalokasidis K; 1st Department of Pharmacology, Faculty of Medicine, Aristotle University of Thessaloniki, Thessaloniki, Greece. Electronic address: kkalokas@gmail.com.
Poulios C; Department of Anatomic Pathology, Faculty of Medicine, Aristotle University of Thessaloniki, Thessaloniki, Greece. Electronic address: dr.poulios@hotmail.com.
Dedi H; 1st Department of Pharmacology, Faculty of Medicine, Aristotle University of Thessaloniki, Thessaloniki, Greece. Electronic address: chntenti@gmail.com.
Karkavelas G; Department of Anatomic Pathology, Faculty of Medicine, Aristotle University of Thessaloniki, Thessaloniki, Greece. Electronic address: gkarkav@med.auth.gr.
Mirtsou V; 1st Department of Pharmacology, Faculty of Medicine, Aristotle University of Thessaloniki, Thessaloniki, Greece. Electronic address: mirtsou@auth.gr.
Goulas A; 1st Department of Pharmacology, Faculty of Medicine, Aristotle University of Thessaloniki, Thessaloniki, Greece. Electronic address: goulas@med.auth.gr.

Pharmacol Rep ; 66(6): 952-5, 2014 Dec.

Article en En | MEDLINE | ID: mdl-25443720

Asunto(s)

Ciproheptadina/análogos & derivados; Histamina/metabolismo; Receptor de Bradiquinina B2/genética; Receptores Histamínicos H1/genética; Animales; Ciproheptadina/farmacología; Edema/prevención & control; Regulación de la Expresión Génica/efectos de los fármacos; Antagonistas de los Receptores Histamínicos H1/farmacología; Ratas; Reacción en Cadena en Tiempo Real de la Polimerasa; Receptor de Bradiquinina B1/genética; Regulación hacia Arriba/efectos de los fármacos

Palabras clave

Bradykinin receptors; Gene expression; Histamine H1 receptor; Rat paw; Rupatadine

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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Receptores Histamínicos H1 / Histamina / Ciproheptadina / Receptor de Bradiquinina B2 Límite: Animals Idioma: En Revista: Pharmacol Rep Asunto de la revista: FARMACOLOGIA Año: 2014 Tipo del documento: Article Pais de publicación: Suiza

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