Your browser doesn't support javascript.
loading
Effects of phonophoresis and gold nanoparticles in experimental model of muscle overuse: role of oxidative stress.
Zortéa, Diogo; Silveira, Paulo C L; Souza, Priscila S; Fidelis, Giulia S P; Paganini, Carla S; Pozzi, Bruna G; Tuon, Talita; De Souza, Claudio T; Paula, Marcos M S; Pinho, Ricardo A.
Afiliación
  • Zortéa D; Laboratory of Physiology and Biochemistry of Exercise, PPGCS, Universidade do Extremo Sul Catarinense, Criciúma, Brazil.
  • Silveira PC; Laboratory of Physiology and Biochemistry of Exercise, PPGCS, Universidade do Extremo Sul Catarinense, Criciúma, Brazil.
  • Souza PS; Laboratory of Physiology and Biochemistry of Exercise, PPGCS, Universidade do Extremo Sul Catarinense, Criciúma, Brazil.
  • Fidelis GS; Laboratory of Physiology and Biochemistry of Exercise, PPGCS, Universidade do Extremo Sul Catarinense, Criciúma, Brazil.
  • Paganini CS; Laboratory of Physiology and Biochemistry of Exercise, PPGCS, Universidade do Extremo Sul Catarinense, Criciúma, Brazil.
  • Pozzi BG; Laboratory of Physiology and Biochemistry of Exercise, PPGCS, Universidade do Extremo Sul Catarinense, Criciúma, Brazil.
  • Tuon T; Laboratory of Physiology and Biochemistry of Exercise, PPGCS, Universidade do Extremo Sul Catarinense, Criciúma, Brazil.
  • De Souza CT; Laboratory of Physiology and Biochemistry of Exercise, PPGCS, Universidade do Extremo Sul Catarinense, Criciúma, Brazil.
  • Paula MM; Laboratory of Synthesis of Multifunctional Complexes, PPGCS, Universidade do Extremo Sul Catarinense, Criciúma, Brazil.
  • Pinho RA; Laboratory of Physiology and Biochemistry of Exercise, PPGCS, Universidade do Extremo Sul Catarinense, Criciúma, Brazil. Electronic address: ap@unesc.net.
Ultrasound Med Biol ; 41(1): 151-62, 2015 Jan.
Article en En | MEDLINE | ID: mdl-25438848
The aim of the study described here was to investigate the effects of pulsed ultrasound and gold nanoparticles (AuNPs) on behavioral, inflammatory and oxidative stress parameters in an experimental model of overuse. Wistar rats performed 21 d of exercise on a treadmill at different intensities and were exposed to ultrasound in the presence or absence of AuNPs. The overuse model promoted behavioral changes and increased creatine kinase, superoxide dismutase and glutathione peroxidase activity, as well as the levels of superoxide, nitrotyrosine, nitric oxide, thiobarbituric acid reactive substance, carbonyl, tumor necrosis factor α and interleukin-6. These values were significantly decreased by AuNPs and by AuNPs plus ultrasound. Catalase activity remained unchanged and the glutathione level increased significantly after exposure to AuNPs plus ultrasound. These results suggest a susceptibility to anxiety as well as elevated levels of oxidative stress. However, therapeutic interventions with AuNPs plus ultrasound reduced the production of oxidants and oxidative damage and improved the anti-oxidant defense system.
Asunto(s)
Palabras clave
Texto completo
Añadir a Mi BVS
Imprimir
XML
PubMed Links
Buscar en Google

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Terapia por Ultrasonido / Trastornos de Traumas Acumulados / Especies Reactivas de Oxígeno / Oro / Enfermedades Musculares Tipo de estudio: Prognostic_studies Límite: Animals Idioma: En Revista: Ultrasound Med Biol Año: 2015 Tipo del documento: Article País de afiliación: Brasil Pais de publicación: Reino Unido
Texto completo
Añadir a Mi BVS
Imprimir
XML
PubMed Links
Buscar en Google

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Terapia por Ultrasonido / Trastornos de Traumas Acumulados / Especies Reactivas de Oxígeno / Oro / Enfermedades Musculares Tipo de estudio: Prognostic_studies Límite: Animals Idioma: En Revista: Ultrasound Med Biol Año: 2015 Tipo del documento: Article País de afiliación: Brasil Pais de publicación: Reino Unido