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Inhibition of Aurora kinase B is important for biologic activity of the dual inhibitors of BCR-ABL and Aurora kinases R763/AS703569 and PHA-739358 in BCR-ABL transformed cells.
Illert, Anna L; Seitz, Anna K; Rummelt, Christoph; Kreutmair, Stefanie; Engh, Richard A; Goodstal, Samantha; Peschel, Christian; Duyster, Justus; von Bubnoff, Nikolas.
Afiliación
  • Illert AL; Clinic for Internal Medicine 1, Hematology, Oncology and Stem Cell Transplantation, Freiburg University Medical Center, 79106 Freiburg, Germany.
  • Seitz AK; Department of Internal Medicine III, Technical University of Munich, 81675 Munich, Germany.
  • Rummelt C; Clinic for Internal Medicine 1, Hematology, Oncology and Stem Cell Transplantation, Freiburg University Medical Center, 79106 Freiburg, Germany.
  • Kreutmair S; Clinic for Internal Medicine 1, Hematology, Oncology and Stem Cell Transplantation, Freiburg University Medical Center, 79106 Freiburg, Germany.
  • Engh RA; The Norwegian Structural Biology Centre, Departments of Chemistry and Pharmacy, University of Tromsø, Tromsø, Norway.
  • Goodstal S; EMD-Serono Research and Development Institute, Inc., Billerica, Massachusetts, United States of America.
  • Peschel C; Department of Internal Medicine III, Technical University of Munich, 81675 Munich, Germany.
  • Duyster J; Clinic for Internal Medicine 1, Hematology, Oncology and Stem Cell Transplantation, Freiburg University Medical Center, 79106 Freiburg, Germany.
  • von Bubnoff N; Clinic for Internal Medicine 1, Hematology, Oncology and Stem Cell Transplantation, Freiburg University Medical Center, 79106 Freiburg, Germany.
PLoS One ; 9(11): e112318, 2014.
Article en En | MEDLINE | ID: mdl-25426931
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Pirazoles / Pirimidinas / Benzamidas / Proteínas de Fusión bcr-abl / Inhibidores de Proteínas Quinasas / Aurora Quinasa B / Antineoplásicos / Norbornanos Límite: Animals / Humans Idioma: En Revista: PLoS One Asunto de la revista: CIENCIA / MEDICINA Año: 2014 Tipo del documento: Article País de afiliación: Alemania Pais de publicación: Estados Unidos
Texto completo
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Pirazoles / Pirimidinas / Benzamidas / Proteínas de Fusión bcr-abl / Inhibidores de Proteínas Quinasas / Aurora Quinasa B / Antineoplásicos / Norbornanos Límite: Animals / Humans Idioma: En Revista: PLoS One Asunto de la revista: CIENCIA / MEDICINA Año: 2014 Tipo del documento: Article País de afiliación: Alemania Pais de publicación: Estados Unidos