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Lower facial remodeling with botulinum toxin type A for the treatment of masseter hypertrophy.
Klein, Fernanda Homem de Mello de Souza; Brenner, Fabiane Mulinari; Sato, Maurício Shigeru; Robert, Fernanda Manfron Batista Rosas; Helmer, Karin Adriane.
Afiliación
  • Klein FH; Private practice particular - Criciúma (SC), Brazil, Criciúma, SC, Brazil.
  • Brenner FM; Universidade Federal do Paraná, Curitiba, PR, Brazil.
  • Sato MS; Universidade Federal do Paraná, Curitiba, PR, Brazil.
  • Robert FM; Universidade Federal do Paraná, Curitiba, PR, Brazil.
  • Helmer KA; Universidade Federal do Paraná, Curitiba, PR, Brazil.
An Bras Dermatol ; 89(6): 878-84, 2014.
Article en En | MEDLINE | ID: mdl-25387491
BACKGROUND: Masseter hypertrophy has been treated with botulinum toxin injections because of esthetic complaints especially in Asians. OBJECTIVES: The goal of the present study was to evaluate the efficacy of abobotulin toxin use in masseter hipertrophy treatment in Brazilians. METHODS: Ten Brazilian female patients with masseter hypertrophy were subjected to injections of 90U of abobotulinum toxin A applied on each side respecting the safety zone stabilished in literature and were followed up for 24 weeks. RESULTS: When analyzing the coefficients between measures of middle and lower third of the face obtained from standardized photographs, an increase was observed, with statistical significance at 2 weeks (p=0.005) and 12 weeks (p=0.001). The progression of lower third reduction was 3.94%, 5.26%, 11.99%, and 5.47% (2, 4, 12, and 24 weeks respectively). All patients showed improvement in bruxism after treatment. Observed adverse effects were masticatory fatigue, smile limitation, and smile asymmetry. CONCLUSION: The use of abobotulinum toxin A for masseter hypertrophy is effective in Brazilians and reached its maximum effect of facial thinning at 12 weeks. Smile limitation had a higher incidence compared to that reported in the literature and may result from risorius muscle blockage caused by toxin dissemination. Despite its side effects, 80% of the patients would like to repeat the treatment.
Asunto(s)

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Toxinas Botulínicas Tipo A / Hipertrofia / Músculo Masetero / Fármacos Neuromusculares Tipo de estudio: Evaluation_studies Límite: Adult / Female / Humans País/Región como asunto: America do sul / Brasil Idioma: En Revista: An Bras Dermatol Año: 2014 Tipo del documento: Article País de afiliación: Brasil Pais de publicación: España

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Toxinas Botulínicas Tipo A / Hipertrofia / Músculo Masetero / Fármacos Neuromusculares Tipo de estudio: Evaluation_studies Límite: Adult / Female / Humans País/Región como asunto: America do sul / Brasil Idioma: En Revista: An Bras Dermatol Año: 2014 Tipo del documento: Article País de afiliación: Brasil Pais de publicación: España