Arterias Cerebrales/fisiopatología; Circulación Cerebrovascular; Enfermedad de Parkinson/diagnóstico; Enfermedad de Parkinson/fisiopatología; Marcadores de Spin; Anciano; Tiempo de Circulación Sanguínea/métodos; Circulación Cerebrovascular/fisiología; Femenino; Humanos; Masculino; Persona de Mediana Edad; Factores de Tiempo

3T, 3 Tesla; AAT, arterial arrival time; AD, Alzheimer's disease; ASL, arterial spin labelling; Arterial arrival time; Arterial spin labelling; CBF, cerebral blood flow; CO2, carbon dioxide; CV, cerebrovascular; CVD, cerebrovascular disease; CVR, cerebrovascular reactivity; CVRAAT, cerebrovascular reactivity measures of arterial arrival time; CVRCBF, cerebrovascular reactivity measures of cerebral blood flow; Cerebral blood flow; Cerebrovascular reactivity; DS, digit span; DSST, digit symbol substitution test; DWMH, deep white matter hyperintensity; EPI, echo planar imaging; ETCO2, end-tidal carbon dioxide; FAS, (verbal) fluency assessment scale; FLAIR, fluid attenuation inversion recovery; FWE, family-wise error; HAM-D, Hamilton depression rating scale; IPD, idiopathic Parkinson's disease; Idiopathic Parkinson's disease; L-dopa, levodopa; LARS, Lille apathy rating scale; LEDD, levodopa equivalent daily dose; MCI, mild cognitive impairment; MRI, magnetic resonance imaging; MoCA; MoCA, Montreal cognitive assessment; NPI, neuropsychiatric inventory; NVU, Neurovascular unit; O2−, oxygen; PET, positron emission tomography; PIGD, Postural instability and gait disorder; PL, parietal lobe; PVH, periventricular hyperintensity; ROI, region of interest; SPECT, single positron emission computed tomography; SPM, statistical parametric mapping; STAR, signal targeting with alternating radiofrequency; TD, tremor dominant; TE, echo time; TI, inversion time; TL, temporal lobe; TMT-B, trail making test B; TR, repetition time; UKPDS BB, United Kingdom Parkinson's Disease Society Brain Bank; UPDRS, Unified Parkinson's disease Rating Scale; WAIS-R, Wechsler adult intelligence scale-revised; WML, white matter lesion; fMRI, functional magnetic resonance imaging