Myocardial performance index in fetal anemia.
Prenat Diagn
; 35(2): 192-6, 2015 Feb.
Article
en En
| MEDLINE
| ID: mdl-25377887
OBJECTIVE: The objective of the study was to examine the correlation between fetal myocardial performance index (MPI) and hemoglobin (Hb) levels. METHODS: It is a prospective study involving singleton pregnancies at risk of fetal anemia as a result of maternal anti-D alloimmune disease. Right and left ventricle (LV) MPIs were evaluated by ultrasound up to 72 h before cordocentesis. Zeta-score values for fetal MPI and Hb levels were calculated, and correlation was examined with linear regression analysis. Significance level was set as 0.05. RESULTS: Fourteen singleton pregnancies underwent 31 cordocentesis procedures at a mean gestation of 28.2 ± 4.1 weeks. Zeta-score values for LV MPI, isovolumetric relaxation time (IRT), and ejection time (ET) correlated significantly with fetal Hb zeta-score (LV MPI zeta = 3.816 + 0.336 × Hb zeta, r = 0.59, p < 0.001; LV IRT zeta = 2.643 + 0.218 × Hb zeta, r = 0.45, p = 0.01; LV ET zeta = -2.474 - 0.271 × Hb zeta, r = -0.42, p = 0.02). LV isovolumetric contraction time (ICT) zeta-score and right ventricle (RV) MPI did not show significant correlation (LV ICT zeta, r = 0.35, p = 0.054; RV MPI, r = 0.12, p = 0.53). CONCLUSION: LV myocardial performance not only remains preserved but also is actually enhanced in cases of moderate/severe fetal anemia.
Texto completo:
1
Colección:
01-internacional
Base de datos:
MEDLINE
Asunto principal:
Enfermedades Fetales
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Corazón
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Anemia
Tipo de estudio:
Observational_studies
/
Risk_factors_studies
Límite:
Adult
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Female
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Humans
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Pregnancy
Idioma:
En
Revista:
Prenat Diagn
Año:
2015
Tipo del documento:
Article
País de afiliación:
Brasil
Pais de publicación:
Reino Unido