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Antitumor activity of the MEK inhibitor TAK-733 against melanoma cell lines and patient-derived tumor explants.
Micel, Lindsey N; Tentler, John J; Tan, Aik-Choon; Selby, Heather M; Brunkow, Kelsey L; Robertson, Kelli M; Davis, S Lindsey; Klauck, Peter J; Pitts, Todd M; Gangolli, Esha; Fabrey, Robyn; O'Connell, Shawn M; Vincent, Patrick W; Eckhardt, S Gail.
Afiliación
  • Micel LN; Division of Medical Oncology, University of Colorado, Anschutz Medical Campus, Aurora, Colorado. Division of Pediatric Hematology/Oncology, Children's Hospital Colorado, Anschutz Medical Campus, Aurora, Colorado.
  • Tentler JJ; Division of Medical Oncology, University of Colorado, Anschutz Medical Campus, Aurora, Colorado. john.tentler@ucdenver.edu.
  • Tan AC; Division of Medical Oncology, University of Colorado, Anschutz Medical Campus, Aurora, Colorado.
  • Selby HM; Division of Medical Oncology, University of Colorado, Anschutz Medical Campus, Aurora, Colorado.
  • Brunkow KL; Division of Medical Oncology, University of Colorado, Anschutz Medical Campus, Aurora, Colorado.
  • Robertson KM; Division of Medical Oncology, University of Colorado, Anschutz Medical Campus, Aurora, Colorado.
  • Davis SL; Division of Medical Oncology, University of Colorado, Anschutz Medical Campus, Aurora, Colorado.
  • Klauck PJ; Division of Medical Oncology, University of Colorado, Anschutz Medical Campus, Aurora, Colorado.
  • Pitts TM; Division of Medical Oncology, University of Colorado, Anschutz Medical Campus, Aurora, Colorado.
  • Gangolli E; Takeda Pharmaceuticals, Inc., Cambridge, Massachusetts.
  • Fabrey R; Takeda Pharmaceuticals, Inc., San Diego, California.
  • O'Connell SM; Takeda Pharmaceuticals, Inc., San Diego, California.
  • Vincent PW; Takeda Pharmaceuticals, Inc., San Diego, California.
  • Eckhardt SG; Division of Medical Oncology, University of Colorado, Anschutz Medical Campus, Aurora, Colorado.
Mol Cancer Ther ; 14(2): 317-25, 2015 Feb.
Article en En | MEDLINE | ID: mdl-25376610
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Piridonas / Pirimidinonas / Inhibidores de Proteínas Quinasas / Melanoma / Antineoplásicos Límite: Animals / Female / Humans Idioma: En Revista: Mol Cancer Ther Asunto de la revista: ANTINEOPLASICOS Año: 2015 Tipo del documento: Article Pais de publicación: Estados Unidos
Texto completo
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Piridonas / Pirimidinonas / Inhibidores de Proteínas Quinasas / Melanoma / Antineoplásicos Límite: Animals / Female / Humans Idioma: En Revista: Mol Cancer Ther Asunto de la revista: ANTINEOPLASICOS Año: 2015 Tipo del documento: Article Pais de publicación: Estados Unidos