Assessment of gene promoter G­quadruplex binding and modulation by a naphthalene diimide derivative in tumor cells.

Nadai, Matteo; Cimino-Reale, Graziella; Sattin, Giovanna; Doria, Filippo; Butovskaya, Elena; Zaffaroni, Nadia; Freccero, Mauro; Palumbo, Manlio; Richter, Sara N; Folini, Marco

Assessment of gene promoter Gquadruplex binding and modulation by a naphthalene diimide derivative in tumor cells.

Nadai, Matteo; Cimino-Reale, Graziella; Sattin, Giovanna; Doria, Filippo; Butovskaya, Elena; Zaffaroni, Nadia; Freccero, Mauro; Palumbo, Manlio; Richter, Sara N; Folini, Marco.

Afiliación

Nadai M; Department of Molecular Medicine, University of Padova, 35121 Padova, Italy.
Cimino-Reale G; Department of Experimental Oncology and Molecular Medicine, Fondazione IRCCS Istituto Nazionale dei Tumori, 20133 Milan, Italy.
Sattin G; Department of Molecular Medicine, University of Padova, 35121 Padova, Italy.
Doria F; Department of Organic Chemistry, University of Pavia, 27100 Pavia, Italy.
Butovskaya E; Department of Molecular Medicine, University of Padova, 35121 Padova, Italy.
Zaffaroni N; Department of Experimental Oncology and Molecular Medicine, Fondazione IRCCS Istituto Nazionale dei Tumori, 20133 Milan, Italy.
Freccero M; Department of Organic Chemistry, University of Pavia, 27100 Pavia, Italy.
Palumbo M; Department of Pharmaceutical and Pharmacological Sciences, University of Padova, 35131 Padova, Italy.
Richter SN; Department of Molecular Medicine, University of Padova, 35121 Padova, Italy.
Folini M; Department of Experimental Oncology and Molecular Medicine, Fondazione IRCCS Istituto Nazionale dei Tumori, 20133 Milan, Italy.

Int J Oncol ; 46(1): 369-80, 2015 Jan.

Article en En | MEDLINE | ID: mdl-25370864

Asunto(s)

Antineoplásicos/farmacología; G-Cuádruplex; Imidas/farmacología; Naftalenos/farmacología; Neoplasias/patología; Oncogenes; Regiones Promotoras Genéticas; Sitios de Unión/efectos de los fármacos; Sitios de Unión/genética; Línea Celular Tumoral; Proliferación Celular/efectos de los fármacos; G-Cuádruplex/efectos de los fármacos; Regulación Neoplásica de la Expresión Génica/efectos de los fármacos; Humanos; Neoplasias/genética; Oncogenes/efectos de los fármacos; Oncogenes/genética; Regiones Promotoras Genéticas/efectos de los fármacos; Regiones Promotoras Genéticas/genética; Telómero/efectos de los fármacos; Telómero/metabolismo

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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Oncogenes / Regiones Promotoras Genéticas / G-Cuádruplex / Imidas / Naftalenos / Neoplasias / Antineoplásicos Límite: Humans Idioma: En Revista: Int J Oncol Asunto de la revista: NEOPLASIAS Año: 2015 Tipo del documento: Article País de afiliación: Italia Pais de publicación: Grecia

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