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Normal values and clinical relevance of left atrial myocardial function analysed by speckle-tracking echocardiography: multicentre study.
Morris, Daniel A; Takeuchi, Masaaki; Krisper, Maximilian; Köhncke, Clemens; Bekfani, Tarek; Carstensen, Tim; Hassfeld, Sabine; Dorenkamp, Marc; Otani, Kyoko; Takigiku, Kiyohiro; Izumi, Chisato; Yuda, Satoshi; Sakata, Konomi; Ohte, Nobuyuki; Tanabe, Kazuaki; Osmanoglou, Engin; Kühnle, York; Düngen, Hans-Dirk; Nakatani, Satoshi; Otsuji, Yutaka; Haverkamp, Wilhelm; Boldt, Leif-Hendrik.
Afiliación
  • Morris DA; Department of Cardiology, Charité University Hospital (Campus Virchow Klinikum, Charité - Universitätsmedizin Berlin), Augustenburger Platz 1, 13353 Berlin, Germany daniel-armando.morris@charite.de.
  • Takeuchi M; School of Medicine, University of Occupational and Environmental Health, Kitakyushu, Japan.
  • Krisper M; Department of Cardiology, Charité University Hospital (Campus Virchow Klinikum, Charité - Universitätsmedizin Berlin), Augustenburger Platz 1, 13353 Berlin, Germany.
  • Köhncke C; Department of Cardiology, Charité University Hospital (Campus Virchow Klinikum, Charité - Universitätsmedizin Berlin), Augustenburger Platz 1, 13353 Berlin, Germany.
  • Bekfani T; Department of Cardiology, Charité University Hospital (Campus Virchow Klinikum, Charité - Universitätsmedizin Berlin), Augustenburger Platz 1, 13353 Berlin, Germany.
  • Carstensen T; Department of Cardiology, Charité University Hospital (Campus Virchow Klinikum, Charité - Universitätsmedizin Berlin), Augustenburger Platz 1, 13353 Berlin, Germany.
  • Hassfeld S; Department of Cardiology, Charité University Hospital (Campus Virchow Klinikum, Charité - Universitätsmedizin Berlin), Augustenburger Platz 1, 13353 Berlin, Germany.
  • Dorenkamp M; Department of Cardiology, Charité University Hospital (Campus Virchow Klinikum, Charité - Universitätsmedizin Berlin), Augustenburger Platz 1, 13353 Berlin, Germany.
  • Otani K; School of Medicine, University of Occupational and Environmental Health, Kitakyushu, Japan.
  • Takigiku K; Nagano Children's Hospital, Azumino, Japan.
  • Izumi C; Tenri Hospital, Tenri, Japan.
  • Yuda S; Sapporo Medical University School of Medicine, Sapporo, Japan.
  • Sakata K; Kyorin University School of Medicine, Tokyo, Japan.
  • Ohte N; Nagoya City University Graduate School of Medical Sciences, Nagoya, Japan.
  • Tanabe K; Shimane University Faculty of Medicine, Izumo, Japan.
  • Osmanoglou E; Meoclinic, Berlin, Germany.
  • Kühnle Y; Department of Cardiology, Charité University Hospital (Campus Virchow Klinikum, Charité - Universitätsmedizin Berlin), Augustenburger Platz 1, 13353 Berlin, Germany.
  • Düngen HD; Department of Cardiology, Charité University Hospital (Campus Virchow Klinikum, Charité - Universitätsmedizin Berlin), Augustenburger Platz 1, 13353 Berlin, Germany.
  • Nakatani S; Osaka University Graduate School of Medicine, Suita, Japan.
  • Otsuji Y; School of Medicine, University of Occupational and Environmental Health, Kitakyushu, Japan.
  • Haverkamp W; Department of Cardiology, Charité University Hospital (Campus Virchow Klinikum, Charité - Universitätsmedizin Berlin), Augustenburger Platz 1, 13353 Berlin, Germany.
  • Boldt LH; Department of Cardiology, Charité University Hospital (Campus Virchow Klinikum, Charité - Universitätsmedizin Berlin), Augustenburger Platz 1, 13353 Berlin, Germany.
Eur Heart J Cardiovasc Imaging ; 16(4): 364-72, 2015 Apr.
Article en En | MEDLINE | ID: mdl-25368210
AIMS: The aim of this multicentre study was to determine the normal range and the clinical relevance of the myocardial function of the left atrium (LA) analysed by 2D speckle-tracking echocardiography (2DSTE). METHODS AND RESULTS: We analysed 329 healthy adult subjects prospectively included in 10 centres and a validation group of 377 patients with left ventricular diastolic dysfunction (LVDD). LA myocardial function was analysed by LA strain rate peak during LA contraction (LA-SRa) and LA strain peak during LA relaxation (LA-Strain). The range of values of LA myocardial function in healthy subjects was LA-SRa -2.11 ± 0.61 s(-1) and LA-Strain 45.5 ± 11.4%, and the lowest expected values of these LA analyses (calculated as -1.96 SD from the mean of healthy subjects) were LA-SRa -0.91 s(-1) and LA-Strain 23.1%. Concerning the clinical relevance of these LA myocardial analyses, LA-SRa and LA-Strain detected subtle LA dysfunction in patients with LVDD, even though LA volumetric measurements were normal. In addition, in these patients we found that the functional class (dyspnoea-NYHA classification) was inversely related to both LA-Strain and LA-SRa. CONCLUSION: In the present multicentre study analysing a large cohort of healthy subjects and patients with LVDD, the normal range and the clinical relevance of the myocardial function of the LA using 2DSTE have been determined.
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Interpretación de Imagen Asistida por Computador / Ecocardiografía Doppler / Función del Atrio Izquierdo / Disfunción Ventricular Izquierda / Diástole Tipo de estudio: Clinical_trials / Etiology_studies / Observational_studies / Risk_factors_studies Límite: Adolescent / Adult / Aged / Female / Humans / Male / Middle aged País/Región como asunto: Asia / Europa Idioma: En Revista: Eur Heart J Cardiovasc Imaging Año: 2015 Tipo del documento: Article País de afiliación: Alemania Pais de publicación: Reino Unido
Texto completo
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Interpretación de Imagen Asistida por Computador / Ecocardiografía Doppler / Función del Atrio Izquierdo / Disfunción Ventricular Izquierda / Diástole Tipo de estudio: Clinical_trials / Etiology_studies / Observational_studies / Risk_factors_studies Límite: Adolescent / Adult / Aged / Female / Humans / Male / Middle aged País/Región como asunto: Asia / Europa Idioma: En Revista: Eur Heart J Cardiovasc Imaging Año: 2015 Tipo del documento: Article País de afiliación: Alemania Pais de publicación: Reino Unido