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Fatal Canid Herpesvirus 1 Respiratory Infections in 4 Clinically Healthy Adult Dogs.
Kumar, S; Driskell, E A; Cooley, A J; Jia, K; Blackmon, S; Wan, X-F; Uhl, E W; Saliki, J T; Sanchez, S; Krimer, P M; Hogan, R J.
Afiliación
  • Kumar S; Department of Pathobiology and Population Medicine, College of Veterinary Medicine, Mississippi State University, Mississippi State, MS, USA.
  • Driskell EA; Department of Pathobiology, College of Veterinary Medicine, University of Illinois, Urbana, IL, USA edriskel@illinois.edu cooley@cvm.msstate.edu.
  • Cooley AJ; Department of Pathobiology and Population Medicine, College of Veterinary Medicine, Mississippi State University, Mississippi State, MS, USA.
  • Jia K; Department of Basic Sciences, College of Veterinary University, Mississippi State University, Mississippi State, MS, USA.
  • Blackmon S; Department of Basic Sciences, College of Veterinary University, Mississippi State University, Mississippi State, MS, USA.
  • Wan XF; Department of Basic Sciences, College of Veterinary University, Mississippi State University, Mississippi State, MS, USA.
  • Uhl EW; Department of Pathology, College of Veterinary Medicine, University of Georgia, Athens, GA, USA.
  • Saliki JT; Veterinary Diagnostic Laboratory, College of Veterinary Medicine, University of Georgia, Athens, GA, USA.
  • Sanchez S; Veterinary Diagnostic Laboratory, College of Veterinary Medicine, University of Georgia, Athens, GA, USA.
  • Krimer PM; Veterinary Diagnostic Laboratory, College of Veterinary Medicine, University of Georgia, Athens, GA, USA.
  • Hogan RJ; Department of Veterinary Biosciences and Diagnostic Imaging, College of Veterinary Medicine, University of Georgia, Athens, GA, USA.
Vet Pathol ; 52(4): 681-7, 2015 Jul.
Article en En | MEDLINE | ID: mdl-25358536
Four healthy adult dogs (Golden Retrievers aged 6 years and 9 years, Dalmatian aged 13 years, and Mastiff aged 5 years) developed clinical signs of acute respiratory disease and died within 2 to 7 days of onset of clinical signs. The lungs of the 3 dogs submitted for necropsy were diffusely and severely reddened due to hyperemia and hemorrhage. Microscopic lesions in all dogs were suggestive of acute viral or toxic respiratory damage and varied from acute severe fibrinonecrotic or hemorrhagic bronchopneumonia to fibrinous or necrotizing bronchointerstitial pneumonia. Necropsied dogs also had hemorrhagic rhinitis and tracheitis with necrosis. Virus isolation, transmission electron microscopy, and polymerase chain reaction were used to confirm the presence of canid herpesvirus 1 (CaHV-1) in the lung samples of these dogs. Lung tissues were negative for influenza A virus, canine distemper virus, canine parainfluenza virus, canine respiratory coronavirus, and canine adenovirus 2. Canid herpesvirus 1 has been isolated from cases of acute infectious respiratory disease in dogs but has only rarely been associated with fatal primary viral pneumonia in adult dogs. The cases in the current report document lesions observed in association with CaHV-1 in 4 cases of fatal canine herpesvirus pneumonia in adult dogs.
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Neumonía Viral / Infecciones del Sistema Respiratorio / Herpesvirus Cánido 1 / Infecciones por Herpesviridae / Enfermedades de los Perros Límite: Animals Idioma: En Revista: Vet Pathol Año: 2015 Tipo del documento: Article País de afiliación: Estados Unidos Pais de publicación: Estados Unidos
Texto completo
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Neumonía Viral / Infecciones del Sistema Respiratorio / Herpesvirus Cánido 1 / Infecciones por Herpesviridae / Enfermedades de los Perros Límite: Animals Idioma: En Revista: Vet Pathol Año: 2015 Tipo del documento: Article País de afiliación: Estados Unidos Pais de publicación: Estados Unidos