Defective functionality of HDL particles in familial apoA-I deficiency: relevance of alterations in HDL lipidome and proteome.

Rached, Fabiana; Santos, Raul D; Camont, Laurent; Miname, Marcio H; Lhomme, Marie; Dauteuille, Carolane; Lecocq, Sora; Serrano, Carlos V; Chapman, M John; Kontush, Anatol

Rached, Fabiana; Santos, Raul D; Camont, Laurent; Miname, Marcio H; Lhomme, Marie; Dauteuille, Carolane; Lecocq, Sora; Serrano, Carlos V; Chapman, M John; Kontush, Anatol.

Afiliación

Rached F; National Institute for Health and Medical Research (INSERM), UMR-ICAN 1166, University of Pierre and Marie Curie - Paris 6, Pitié - Salpétrière University Hospital, ICAN, Paris, France Heart Institute-InCor, University of Sao Paulo, Sao Paulo, Brazil.
Santos RD; Heart Institute-InCor, University of Sao Paulo, Sao Paulo, Brazil.
Camont L; National Institute for Health and Medical Research (INSERM), UMR-ICAN 1166, University of Pierre and Marie Curie - Paris 6, Pitié - Salpétrière University Hospital, ICAN, Paris, France.
Miname MH; Heart Institute-InCor, University of Sao Paulo, Sao Paulo, Brazil.
Lhomme M; National Institute for Health and Medical Research (INSERM), UMR-ICAN 1166, University of Pierre and Marie Curie - Paris 6, Pitié - Salpétrière University Hospital, ICAN, Paris, France.
Dauteuille C; National Institute for Health and Medical Research (INSERM), UMR-ICAN 1166, University of Pierre and Marie Curie - Paris 6, Pitié - Salpétrière University Hospital, ICAN, Paris, France.
Lecocq S; National Institute for Health and Medical Research (INSERM), UMR-ICAN 1166, University of Pierre and Marie Curie - Paris 6, Pitié - Salpétrière University Hospital, ICAN, Paris, France.
Serrano CV; Heart Institute-InCor, University of Sao Paulo, Sao Paulo, Brazil.
Chapman MJ; National Institute for Health and Medical Research (INSERM), UMR-ICAN 1166, University of Pierre and Marie Curie - Paris 6, Pitié - Salpétrière University Hospital, ICAN, Paris, France.
Kontush A; National Institute for Health and Medical Research (INSERM), UMR-ICAN 1166, University of Pierre and Marie Curie - Paris 6, Pitié - Salpétrière University Hospital, ICAN, Paris, France.

J Lipid Res ; 55(12): 2509-20, 2014 Dec.

Article en En | MEDLINE | ID: mdl-25341944

Asunto(s)

Apolipoproteína A-I/deficiencia; Apolipoproteína C-III/sangre; Proteínas de Transferencia de Ésteres de Colesterol/sangre; HDL-Colesterol/sangre; Hipoalfalipoproteinemias/sangre; Lipoproteínas HDL/sangre; Adulto; Apolipoproteína A-I/sangre; Apolipoproteína A-I/genética; Apolipoproteína A-I/metabolismo; Apolipoproteína C-III/metabolismo; Brasil; Proteínas de Transferencia de Ésteres de Colesterol/metabolismo; Ésteres del Colesterol/sangre; Ésteres del Colesterol/metabolismo; HDL-Colesterol/metabolismo; LDL-Colesterol/sangre; LDL-Colesterol/metabolismo; Codón sin Sentido; Salud de la Familia; Femenino; Heterocigoto; Homocigoto; Humanos; Hipoalfalipoproteinemias/genética; Hipoalfalipoproteinemias/metabolismo; Lipoproteínas HDL/metabolismo; Lipoproteínas HDL3/sangre; Lipoproteínas HDL3/metabolismo; Masculino; Fosfolípidos/sangre; Fosfolípidos/metabolismo; Esfingolípidos/sangre; Esfingolípidos/metabolismo; Triglicéridos/sangre; Triglicéridos/metabolismo

Palabras clave

HDL functionality; antioxidative activity; apolipoprotein A-I; cellular cholesterol efflux; familial deficiency; genetics; high density lipoprotein; lipidomics

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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Apolipoproteína A-I / Hipoalfalipoproteinemias / Proteínas de Transferencia de Ésteres de Colesterol / Apolipoproteína C-III / Lipoproteínas HDL / HDL-Colesterol Límite: Adult / Female / Humans / Male País/Región como asunto: America do sul / Brasil Idioma: En Revista: J Lipid Res Año: 2014 Tipo del documento: Article País de afiliación: Brasil Pais de publicación: Estados Unidos

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