[Digital ulcers in systemic scleroderma]. / Digitale Ulzerationen bei systemischer Sklerodermie.
Hautarzt
; 65(11): 944-8, 2014 Nov.
Article
en De
| MEDLINE
| ID: mdl-25336296
Digital ulcers (DU's) are one of the main symptoms of systemic scleroderma and occur in approximately 60% of all scleroderma patients. Due to possible complications such as infections, gangrene or amputation, they require regular medical attention and a good wound treatment by doctors and nursing staff. A definition of DU's has not yet been established. In 2009 the European League Against Rheumatism (EULAR) published guidelines for the treatment of DU's. An improvement of the healing of active ulcers has been described with Iloprost. Bosentan significantly reduced the frequency of occurrence of new DU's. In some small studies PDE-5 inhibitors appear helpful. Further studies with other therapeutic approaches will follow in the next few years.
Texto completo:
1
Colección:
01-internacional
Base de datos:
MEDLINE
Asunto principal:
Esclerodermia Sistémica
/
Úlcera Cutánea
/
Sulfonamidas
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Iloprost
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Inhibidores de Fosfodiesterasa 5
Tipo de estudio:
Diagnostic_studies
/
Etiology_studies
/
Guideline
Límite:
Humans
Idioma:
De
Revista:
Hautarzt
Año:
2014
Tipo del documento:
Article
Pais de publicación:
Alemania