[Laboratory surveillance for invasive meningococcal disease in Chile, 2006-2012]. / Vigilancia de laboratorio de enfermedad meningocóccica invasora en Chile, 2006-2012.
Rev Chilena Infectol
; 31(4): 377-84, 2014 Aug.
Article
en Es
| MEDLINE
| ID: mdl-25327189
BACKGROUND: Laboratory surveillance of Invasive Meningococcal Disease (IMD) is performed by the Institute of Public Health of Chile. It confirms identification, classifies in serogroups and analyzes the genetic profiles of Neisseria meningitidis isolates from laboratories throughout the country. AIM: To show the results of this surveillance from 2006 to 2012. METHODS: A descriptive data analysis of the confirmed cases of IMD and serological characterization, susceptibility and genetic profiles of the isolates. The analysis was disaggregated by serogroup, age and region. RESULTS: From 2006 to 2012, 486 isolates of N. meningitidis were confirmed. In 2011 a rise in IMD rates was observed due to an increase in W serogroup cases, mainly affecting children aged 5 years or less. Serogroup W became the most prevalent during 2012 (58.3%), replacing the historically prevalent serogroup B. Predominating strains belonged to ST-32 complex/ET-5 complex (40, 4% of strains) and ST-41/44 complex/ Lineage 3 (45, 9% of strains). CONCLUSIONS: Laboratory surveillance has allowed the early detection of increasing IMD caused by serogroup W, which is emergent in Chile. This information has reinforced the daily monitoring of new cases, in collaboration with all the clinical laboratories of the country.
Texto completo:
1
Colección:
01-internacional
Base de datos:
MEDLINE
Asunto principal:
Vigilancia de la Población
/
Infecciones Meningocócicas
/
Neisseria meningitidis
Tipo de estudio:
Incidence_studies
/
Prognostic_studies
/
Screening_studies
Límite:
Adolescent
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Adult
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Child
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Child, preschool
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Humans
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Infant
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Middle aged
País/Región como asunto:
America do sul
/
Chile
Idioma:
Es
Revista:
Rev Chilena Infectol
Año:
2014
Tipo del documento:
Article
Pais de publicación:
Chile