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Statin use and risk of nonmelanoma skin cancer: a nationwide study in Denmark.
Arnspang, S; Pottegård, A; Friis, S; Clemmensen, O; Andersen, K E; Hallas, J; Gaist, D.
Afiliación
  • Arnspang S; Clinical Pharmacology, Institute of Public Health, University of Southern Denmark, J.B. Winsløws Vej 19, 2.sal, 5000 Odense C, Denmark.
  • Pottegård A; 1] Clinical Pharmacology, Institute of Public Health, University of Southern Denmark, J.B. Winsløws Vej 19, 2.sal, 5000 Odense C, Denmark [2] Department of Clinical Chemistry & Pharmacology, Odense University Hospital, J.B. Winsløws Vej 19, 2.sal, 5000 Odense C, Denmark.
  • Friis S; 1] Danish Cancer Society Research Centre, Strandboulevarden 49, 2100, Copenhagen Ø, Denmark [2] Faculty of Health, Institute of Clinical Medicine, Aarhus University, Aarhus, Denmark [3] Department of Public Health, University of Copenhagen, Copenhagen, Denmark.
  • Clemmensen O; Department of Clinical Pathology, Odense University Hospital, J.B. Winsløws Vej 15, 5000 Odense C, Denmark.
  • Andersen KE; Department of Dermatology and Allergy Centre, Odense University Hospital, Institute of Clinical Research, Faculty of Health Sciences, University of Southern Denmark, Sdr. Boulevard 29, 5000 Odense C, Denmark.
  • Hallas J; 1] Clinical Pharmacology, Institute of Public Health, University of Southern Denmark, J.B. Winsløws Vej 19, 2.sal, 5000 Odense C, Denmark [2] Department of Clinical Chemistry & Pharmacology, Odense University Hospital, J.B. Winsløws Vej 19, 2.sal, 5000 Odense C, Denmark.
  • Gaist D; Department of Neurology, Odense University Hospital, Institute of Clinical Research, Faculty of Health Sciences, University of Southern Denmark, Sdr. Boulevard 29, 5000 Odense C, Denmark.
Br J Cancer ; 112(1): 153-6, 2015 Jan 06.
Article en En | MEDLINE | ID: mdl-25290087
BACKGROUND: Evidence is conflicting regarding statin use and risk of basal cell (BCC) and squamous cell skin cancer (SCC). METHODS: Using Danish nationwide registries, we identified all patients with incident BCC/SCC during 2005-2009 and matched them to population controls. We computed odds ratios (ORs) for BCC and SCC associated with statin use. RESULTS: We identified 38,484 cases of BCC and 3724 cases of SCC. Statin ever use was associated with ORs of 1.09 (CI: 1.06-1.13) for BCC and 1.01 (CI: 0.91-1.11) for SCC. CONCLUSIONS: Statin use was not associated with risk of SCC. Residual confounding plausibly explains the marginally increased risk of BCC.
Asunto(s)

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Neoplasias Cutáneas / Inhibidores de Hidroximetilglutaril-CoA Reductasas Tipo de estudio: Etiology_studies / Observational_studies / Risk_factors_studies Límite: Adult / Aged / Aged80 / Female / Humans / Male / Middle aged País/Región como asunto: Europa Idioma: En Revista: Br J Cancer Año: 2015 Tipo del documento: Article País de afiliación: Dinamarca Pais de publicación: Reino Unido

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Neoplasias Cutáneas / Inhibidores de Hidroximetilglutaril-CoA Reductasas Tipo de estudio: Etiology_studies / Observational_studies / Risk_factors_studies Límite: Adult / Aged / Aged80 / Female / Humans / Male / Middle aged País/Región como asunto: Europa Idioma: En Revista: Br J Cancer Año: 2015 Tipo del documento: Article País de afiliación: Dinamarca Pais de publicación: Reino Unido