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Discovery of substituted 6-pheny-3H-pyridazin-3-one derivatives as novel c-Met kinase inhibitors.
Kang, Seung-Tae; Kim, Eun-Young; Achary, Raghavendra; Jung, Heejung; Park, Chi Hoon; Yun, Chang-Soo; Hwang, Jong Yeon; Choi, Sang Un; Chae, Chonghak; Lee, Chong Ock; Kim, Hyoung Rae; Ha, Jae Du; Ryu, Dohyun; Cho, Sung Yun.
Afiliación
  • Kang ST; Department of Chemistry, Sungkyunkwan University, Suwon 440-746, Republic of Korea.
  • Kim EY; Department of Chemistry, Sungkyunkwan University, Suwon 440-746, Republic of Korea.
  • Achary R; Department of Medicinal and Pharmaceutical Chemistry, University of Science & Technology, Daejeon 305-550, Republic of Korea.
  • Jung H; Drug Discovery Division, Korea Research Institute of Chemical Technology, PO Box 107, Daejeon 305-600, Republic of Korea; Department of Medicinal and Pharmaceutical Chemistry, University of Science & Technology, Daejeon 305-550, Republic of Korea.
  • Park CH; Drug Discovery Division, Korea Research Institute of Chemical Technology, PO Box 107, Daejeon 305-600, Republic of Korea; Department of Medicinal and Pharmaceutical Chemistry, University of Science & Technology, Daejeon 305-550, Republic of Korea.
  • Yun CS; Drug Discovery Division, Korea Research Institute of Chemical Technology, PO Box 107, Daejeon 305-600, Republic of Korea; Department of Medicinal and Pharmaceutical Chemistry, University of Science & Technology, Daejeon 305-550, Republic of Korea.
  • Hwang JY; Drug Discovery Division, Korea Research Institute of Chemical Technology, PO Box 107, Daejeon 305-600, Republic of Korea; Department of Medicinal and Pharmaceutical Chemistry, University of Science & Technology, Daejeon 305-550, Republic of Korea.
  • Choi SU; Drug Discovery Division, Korea Research Institute of Chemical Technology, PO Box 107, Daejeon 305-600, Republic of Korea.
  • Chae C; Drug Discovery Division, Korea Research Institute of Chemical Technology, PO Box 107, Daejeon 305-600, Republic of Korea.
  • Lee CO; Drug Discovery Division, Korea Research Institute of Chemical Technology, PO Box 107, Daejeon 305-600, Republic of Korea.
  • Kim HR; Drug Discovery Division, Korea Research Institute of Chemical Technology, PO Box 107, Daejeon 305-600, Republic of Korea.
  • Ha JD; Drug Discovery Division, Korea Research Institute of Chemical Technology, PO Box 107, Daejeon 305-600, Republic of Korea. Electronic address: jdha@krict.re.kr.
  • Ryu D; Department of Chemistry, Sungkyunkwan University, Suwon 440-746, Republic of Korea.
  • Cho SY; Drug Discovery Division, Korea Research Institute of Chemical Technology, PO Box 107, Daejeon 305-600, Republic of Korea; Department of Medicinal and Pharmaceutical Chemistry, University of Science & Technology, Daejeon 305-550, Republic of Korea. Electronic address: sycho@krict.re.kr.
Bioorg Med Chem Lett ; 24(21): 5093-7, 2014 11 01.
Article en En | MEDLINE | ID: mdl-25282552
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Piridazinas / Proteínas Proto-Oncogénicas c-met / Inhibidores de Proteínas Quinasas Límite: Humans Idioma: En Revista: Bioorg Med Chem Lett Asunto de la revista: BIOQUIMICA / QUIMICA Año: 2014 Tipo del documento: Article Pais de publicación: Reino Unido
Texto completo
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Piridazinas / Proteínas Proto-Oncogénicas c-met / Inhibidores de Proteínas Quinasas Límite: Humans Idioma: En Revista: Bioorg Med Chem Lett Asunto de la revista: BIOQUIMICA / QUIMICA Año: 2014 Tipo del documento: Article Pais de publicación: Reino Unido